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Clinical effect of toothpaste and mouth rinse containing zinc lactate on oral malodor reduction

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Clinical effect of toothpaste and mouth rinse containing zinc lactate on oral malodor reduction

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dc.contributor.author Srisilapanan, Patcharawan es
dc.contributor.author Roseman, Jeffrey es
dc.contributor.author Likitsatian, Tanrada es
dc.date.accessioned 2019-07-02T09:25:00Z
dc.date.available 2019-07-02T09:25:00Z
dc.date.issued 2019 es
dc.identifier.citation Srisilapanan, Patcharawan ; Roseman, Jeffrey ; Likitsatian, Tanrada. Clinical effect of toothpaste and mouth rinse containing zinc lactate on oral malodor reduction. En: Journal of Clinical and Experimental Dentistry, 11 4 2019: 346-352 es
dc.identifier.uri https://hdl.handle.net/10550/70644
dc.description.abstract This study aimed to investigate the effect of toothpaste and mouth rinse containing 0.14% zinc lactate on the reduction of three volatile oral malodor gases. Ten subjects with good health were recruited to take part in a crossover design study with a 7-day washout period. They were randomly assigned to use the test (toothpaste and rinse containing 0.14% zinc lactate) or placebo (negative control) treatment regimens within the two-week period. All subjects were asked to refrain from tooth brushing and eating in the morning prior to the gas collection periods. The assessment of malodor measured the quantity of three volatile sulphur compounds (VSCs) using an OralChromaTM device. Oral gas collecting was divided into four time periods; before breakfast and the morning oral hygiene practice (baseline); after oral hygiene at 30 minutes, 1 hour and 2 hours. After the baseline assessment, each subject used the test or placebo treatment regimen for 7 days. After 7 and 14 days, subjects returned to the study site to repeat the same procedures with different products. Kruskal-Wallis was used to analyze the mean differences of malodor gases between the two test regimens. The baseline mean of total VSCs in test and control groups was 6.5±3.7 and 1.7±9.3 ng/10 ml, respectively. The percent reduction of H2S at 30 minutes, 1 hour and 2 hours was statistically significant (p<0.005) in both treatments. The percent reduction of (CH3)2S and total VSCs in both treatments after 1 hour was statistically significant (p<0.005). The test treatment regimen was more effective than the placebo treatment regimen. es
dc.title Clinical effect of toothpaste and mouth rinse containing zinc lactate on oral malodor reduction es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.55418 es
dc.type.hasVersion VoR es_ES

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