NAGIOS: RODERIC FUNCIONANDO

Benign epithelial oral lesions ? association with human papillomavirus

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Benign epithelial oral lesions ? association with human papillomavirus

Mostra el registre parcial de l'element

dc.contributor.author Piña, Alicia-Rumayor es
dc.contributor.author Fonseca, Felipe Paiva es
dc.contributor.author Corrêa Pontes, Flávia Sirotheau es
dc.contributor.author Rebelo-Pontes, Hélder-Antônio es
dc.contributor.author Pires, Fábio-Ramôa es
dc.contributor.author Mosqueda Taylor, Adalberto es
dc.contributor.author Aguirre Urízar, José Manuel es
dc.contributor.author Almeida, Oslei Paes de es
dc.date.accessioned 2019-07-02T09:56:00Z
dc.date.available 2019-07-02T09:56:00Z
dc.date.issued 2019 es
dc.identifier.citation Piña, Alicia-Rumayor ; Fonseca, Felipe Paiva ; Corrêa Pontes, Flávia Sirotheau ; Rebelo-Pontes, Hélder-Antônio ; Pires, Fábio-Ramôa ; Mosqueda Taylor, Adalberto ; Aguirre Urízar, José Manuel ; Almeida, Oslei Paes de. Benign epithelial oral lesions ? association with human papillomavirus. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 24 3 2019: 13- es
dc.identifier.uri https://hdl.handle.net/10550/70677
dc.description.abstract The presence of human papilloma virus in benign oral lesions has been studied by different techniques obtaining extremely variable results. The objective of this study was to determine the presence of human papillomavirus in 83 cases of benign hyperplastic epithelial oral lesions. Eighty-three oral lesions with clinical or histopathological features suggestive of HPV infection were retrieved from the files of four oral pathology services. Demographic data were obtained from patient´s medical charts. All cases had available clinical image, H&E preparations and paraffin blocks with enough tissue for HPV detection by in situ hybridization, and immunohistochemical reactions for Ki67. Episomal positivity for wide spectrum HPV was observed in 24% of the cases; most of them (70%) HPV 6/11 positive. HPV 16/18 was not detected. Condyloma acuminatum was the most common lesion associated with HPV (75%), followed by verruca vulgaris (15%), squamous papilloma and multifocal epithelial hyperplasia, 5% each. Koilocytes were identified in all the HPV positive cases. Ki67 showed an abnormal proliferation pattern in 90% of the HPV positive cases; most of them (70%) showing groups of proliferating cells in focal superficial regions, and in 20% positivity was seen almost in the whole thickness of the epithelium. HPV negative cases showed Ki67 positive cells restricted to the basal layer. Regarding oral lesions associated with HPV, condyloma is the most common lesion expressing low-risk subtypes. The etiology of squamous papilloma remains controversial as HPV was found in 1.9% of the cases. The identification of koilocytes and the pattern of expression of Ki67 reflect HPV infection and are helpful for classification. Papillary oral lesions not associated to HPV deserve further studies to better clarify its etiology. es
dc.title Benign epithelial oral lesions ? association with human papillomavirus es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.22817 es
dc.type.hasVersion VoR es_ES

Visualització       (2.657Mb)

Aquest element apareix en la col·lecció o col·leccions següent(s)

Mostra el registre parcial de l'element

Cerca a RODERIC

Cerca avançada

Visualitza

Estadístiques