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Assessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial

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Assessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial

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dc.contributor.author Fons Badal, Carla es
dc.contributor.author Agustín Panadero, Rubén es
dc.contributor.author Solá Ruiz, María Fernanda es
dc.contributor.author Alpiste Illueca, Francisco M. es
dc.contributor.author Fons Font, Antonio es
dc.date.accessioned 2019-11-06T12:51:56Z
dc.date.available 2019-11-06T12:51:56Z
dc.date.issued 2019 es
dc.identifier.citation Fons Badal, Carla ; Agustín Panadero, Rubén ; Solá Ruiz, María Fernanda ; Alpiste Illueca, Francisco M. ; Fons Font, Antonio. Assessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 24 5 2019: 16- es
dc.identifier.uri https://hdl.handle.net/10550/72074
dc.description.abstract This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophosphate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients? subjective perceptive of mouth rinse efficacy. The test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective. The test/B and placebo mouth rinses both modified certain parameters in saliva composition, particularly reductions in urea, uric acid, and phosphorous. Calcium tended to increase after using the test-B mouth rinse. The results did not demonstrate the anticalculus efficacy of the pyrophosphate-based mouth rinse or positive effects on saliva flow or composition. This field requires further research, as no product has been developed that prevents calculus formation completely. es
dc.title Assessment of the capacity of a pyrophosphate-based mouth rinse to inhibit the formation of supragingival dental calculus. a randomized double-blind placebo-controlled clinical trial es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.23036 es
dc.type.hasVersion VoR es_ES

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