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Oral neural tumors : clinicopathologic analysis of 157 cases and review of the literature

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Oral neural tumors : clinicopathologic analysis of 157 cases and review of the literature

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dc.contributor.author Tamiolakis, Paris es
dc.contributor.author Chrysomali, Evanthia es
dc.contributor.author Sklavounou-Andrikopoulou, Alexandra es
dc.contributor.author Nikitakis, Nikolaos G. es
dc.date.accessioned 2019-11-22T12:20:53Z
dc.date.available 2019-11-22T12:20:53Z
dc.date.issued 2019 es
dc.identifier.citation Tamiolakis, Paris ; Chrysomali, Evanthia ; Sklavounou-Andrikopoulou, Alexandra ; Nikitakis, Nikolaos G.. Oral neural tumors : clinicopathologic analysis of 157 cases and review of the literature. En: Journal of Clinical and Experimental Dentistry, 11 8 2019: 721-731 es
dc.identifier.uri https://hdl.handle.net/10550/72305
dc.description.abstract Oral neural tumors (ONTs) are rare lesions and represent reactive or neoplastic proliferations of nerve sheath cells. The purpose of the present study is to report the clinical, demographic and histopathologic features of 157 ONTs diagnosed in a single Oral Pathology Department and review the pertinent literature. 157 cases of ONTs diagnosed during a 44-year period were retrospectively collected and the diagnosis was reconfirmed by studying representative haematoxylin and eosin stained tissue sections. The patients? gender and age, as well as the main clinical features of the lesions, were retrieved from the biopsy submission forms. The 157 ONTs represented approximately 0.4% of 35,590 biopsies accessioned during the study period. They affected 71 male and 86 female patients with a mean age of 38.4±18.8 years. They mainly appeared as asymptomatic nodules of normal or white colour on the tongue, lip mucosa and hard palate. The most common ONT was granular cell tumour (38.9%) followed by neurofibroma (19.7%), schwannoma (15.9%), traumatic neuroma (15.9%), palisaded encapsulated neuroma (8.3%) and nerve sheath myxoma (1.3%). This study confirmed the rarity of ONTs. Their clinical characteristics mimic other oral lesions; thus, microscopic examination is the only mean to arrive at a definitive diagnosis. es
dc.title Oral neural tumors : clinicopathologic analysis of 157 cases and review of the literature es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.55944 es
dc.type.hasVersion VoR es_ES

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