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Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.

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Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.

dc.contributor.author	de Miguel, Lucía
dc.contributor.author	Ferrero, Hortensia
dc.contributor.author	López Martínez, Sara
dc.contributor.author	Campo, Hannes
dc.contributor.author	López Pérez, Nuria
dc.contributor.author	Faus, Amparo
dc.contributor.author	Hervás, David
dc.contributor.author	Santamaría, Xavier
dc.contributor.author	Pellicer, Antonio
dc.contributor.author	Cervelló Alcaraz, Irene
dc.date.accessioned	2020-01-15T11:01:15Z
dc.date.available	2020-01-15T11:01:15Z
dc.date.issued	2020
dc.identifier.citation	de Miguel, Lucía Ferrero, Hortensia López Martínez, Sara Campo, Hannes López Pérez, Nuria Faus, Amparo Hervás, David Santamaría, Xavier Pellicer, Antonio Cervelló Alcaraz, Irene 2020 Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study. BJOG-An International Journal of Obstetrics and Gynaecology
dc.identifier.uri	https://hdl.handle.net/10550/72569
dc.description.abstract	Objective: Determining genetic and paracrine mechanisms behind endometrial regeneration in Asherman's Syndrome and Endometrial Atrophy (AS/EA) patients after autologous CD133+ bone marrow-derived stem cells (CD133+BMDSCs) transplantation. Design: Retrospective study using human endometrial biopsies and mouse models. Setting: Fundación-IVI, IIS-La Fe, Valencia, Spain. Samples: Endometrial biopsies collected before and after CD133+BMDSCs therapy, from 8 women with AS/EA (NCT02144987). And uterus from 5 mice, with only left horns receiving CD133+BMDSCs therapy. Methods: In human samples, hematoxylin and eosin (H&E) staining, RNA arrays, PCR validation and neutrophil elastase (NE) immunohistochemistry (IHQ). In mouse samples, PCR validation and protein immunoarrays.
dc.relation.ispartof	BJOG-An International Journal of Obstetrics and Gynaecology, 2020
dc.title	Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.
dc.type	journal article	es_ES
dc.date.updated	2020-01-15T11:01:15Z
dc.identifier.idgrec	135707
dc.rights.accessRights	open access	es_ES