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pBrain: A novel pipeline for Parkinson related brain structure segmentation

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pBrain: A novel pipeline for Parkinson related brain structure segmentation

dc.contributor.author	Manjón, José Vicente
dc.contributor.author	Bertó, Alexa
dc.contributor.author	Romero, José E.
dc.contributor.author	Lanuza Navarro, Enrique
dc.contributor.author	Vivo-Hernando, Roberto
dc.contributor.author	Aparici Robles, Fernando
dc.contributor.author	Coupé, Pierrick
dc.date.accessioned	2020-03-04T14:56:17Z
dc.date.available	2020-03-04T14:56:17Z
dc.date.issued	2020
dc.identifier.citation	Manjón, José Vicente Bertó, Alexa Romero, José E. Lanuza Navarro, Enrique Vivo-Hernando, Roberto Aparici Robles, Fernando Coupé, Pierrick 2020 pBrain: A novel pipeline for Parkinson related brain structure segmentation Neuroimage-Clinical 25 102184
dc.identifier.uri	https://hdl.handle.net/10550/73412
dc.description.abstract	Parkinson is a very prevalent neurodegenerative disease impacting the life of millions of people worldwide. Although its cause remains unknown, its functional and structural analysis is fundamental to advance in the search of a cure or symptomatic treatment. The automatic segmentation of deep brain structures related to Parkinson`s disease could be beneficial for the follow up and treatment planning. Unfortunately, there is not broadly available segmentation software to automatically measure Parkinson related structures. In this paper, we present a novel pipeline to segment three deep brain structures related to Parkinson's disease (substantia nigra, subthalamic nucleus and red nucleus). The proposed method is based on the multi-atlas label fusion technology that works on standard and high-resolution T2-weighted images. The proposed method also includes as post-processing a new neural network-based error correction step to minimize systematic segmentation errors. The proposed method has been compared to other state-of-the-art methods showing competitive results in terms of accuracy and execution time.
dc.language.iso	eng
dc.relation.ispartof	Neuroimage-Clinical, 2020, vol. 25, p. 102184
dc.subject	Sistema nerviós Malalties
dc.subject	Neurologia
dc.title	pBrain: A novel pipeline for Parkinson related brain structure segmentation
dc.type	journal article	es_ES
dc.date.updated	2020-03-04T14:56:17Z
dc.identifier.doi	10.1016/j.nicl.2020.102184
dc.identifier.idgrec	136586
dc.rights.accessRights	open access	es_ES