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Regulatory Mechanisms of Estrogen on Vascular Ageing

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Regulatory Mechanisms of Estrogen on Vascular Ageing

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Novella del Campo, Susana; Dantas, A. P.; Hermenegildo, Carlos; Hellsten. Ylva

Aquest document és un/a article, creat/da en: 2019

Women can be considered hemodynamically younger than men of the same age, based on epidemiological studies establishing that the incidence of vascular diseases in women is relatively lower compared to that in aged-matched men. However, after menopause, these numbers increase to values that are close to those found in men. Vascular ageing is associated with structural and functional changes of the vascular wall, including endothelial dysfunction, arterial stiffening, and remodelling, as well as impaired angiogenesis, which become major risk factors in the development of cardiovascular disease.

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