NAGIOS: RODERIC FUNCIONANDO

Compact Method for Proton Range Verification Based on Coaxial Prompt Gamma-Ray Monitoring: a Theoretical Study

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Compact Method for Proton Range Verification Based on Coaxial Prompt Gamma-Ray Monitoring: a Theoretical Study

Mostra el registre parcial de l'element

dc.contributor.author Hueso González, Fernando
dc.contributor.author Bortfeld, Thomas
dc.date.accessioned 2020-03-25T08:37:30Z
dc.date.available 2020-03-25T08:37:30Z
dc.date.issued 2020
dc.identifier.citation Hueso González, Fernando Bortfeld, Thomas 2020 Compact Method for Proton Range Verification Based on Coaxial Prompt Gamma-Ray Monitoring: a Theoretical Study IEEE Transactions on Radiation and Plasma Medical Sciences 4 2 170 183
dc.identifier.uri https://hdl.handle.net/10550/73650
dc.description.abstract Range uncertainties in proton therapy hamper treatment precision. Prompt gamma-rays were suggested 16 years ago for real-time range verification, and have already shown promising results in clinical studies with collimated cameras. Simultaneously, alternative imaging concepts without collimation are investigated to reduce the footprint and price of current prototypes. In this paper, a compact range verification method is presented. It monitors prompt gamma-rays with a single scintillation detector positioned coaxially to the beam and behind the patient. Thanks to the solid angle effect, proton range deviations can be derived from changes in the number of gamma-rays detected per proton, provided that the number of incident protons is well known. A theoretical background is formulated and the requirements for a future proof-of-principle experiment are identified. The potential benefits and disadvantages of the method are discussed, and the prospects and potential obstacles for its use during patient treatments are assessed. The final milestone is to monitor proton range differences in clinical cases with a statistical precision of 1 mm, a material cost of 25000 USD and a weight below 10 kg. This technique could facilitate the widespread application of in vivo range verification in proton therapy and eventually the improvement of treatment quality.
dc.language.iso eng
dc.relation.ispartof IEEE Transactions on Radiation and Plasma Medical Sciences, 2020, vol. 4, num. 2, p. 170-183
dc.subject Radiació
dc.subject Detectors de radiació
dc.title Compact Method for Proton Range Verification Based on Coaxial Prompt Gamma-Ray Monitoring: a Theoretical Study
dc.type journal article es_ES
dc.date.updated 2020-03-25T08:37:30Z
dc.identifier.doi 10.1109/TRPMS.2019.2930362
dc.identifier.idgrec 137181
dc.rights.accessRights open access es_ES

Visualització       (1.577Mb)

Aquest element apareix en la col·lecció o col·leccions següent(s)

Mostra el registre parcial de l'element

Cerca a RODERIC

Cerca avançada

Visualitza

Estadístiques