NAGIOS: RODERIC FUNCIONANDO

Microparticles Harboring Sonic Hedgehog Morphogen Improve the Vasculogenesis Capacity of Endothelial Progenitor Cells Derived from Myocardial Infarction Patients.

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Microparticles Harboring Sonic Hedgehog Morphogen Improve the Vasculogenesis Capacity of Endothelial Progenitor Cells Derived from Myocardial Infarction Patients.

dc.contributor.author	Bueno-Betí, C
dc.contributor.author	Novella, S
dc.contributor.author	Soleti, R
dc.contributor.author	Mompeón, A
dc.contributor.author	Vergori, L
dc.contributor.author	Sanchís Fores, Juan
dc.contributor.author	Andriantsitohaina, R
dc.contributor.author	Martínez, MC
dc.contributor.author	Hermenegildo, Carlos
dc.date.accessioned	2020-03-27T09:04:46Z
dc.date.available	2020-03-27T09:04:46Z
dc.date.issued	2019
dc.identifier.citation	Bueno-Betí, C Novella, S Soleti, R Mompeón, A Vergori, L Sanchís Fores, Juan Andriantsitohaina, R Martínez, MC Hermenegildo, Carlos 2019 Microparticles Harboring Sonic Hedgehog Morphogen Improve the Vasculogenesis Capacity of Endothelial Progenitor Cells Derived from Myocardial Infarction Patients. Cardiovascular research 115 2 409 418
dc.identifier.uri	https://hdl.handle.net/10550/73680
dc.description.abstract	Endothelial progenitor cells (EPC) play a role in endothelium integrity maintenance and regeneration. Decreased numbers of EPC or their impaired function correlates with an increase in cardiovascular events. Thus, EPC are important predictors of cardiovascular mortality and morbidity. Microparticles carrying Sonic hedgehog (Shh) morphogen (MPShhþ) trigger pro-angiogenic responses, both in endothelial cells and in ischaemic rodent models. Here, we propose that MPShhþ regulates EPC function, thus enhancing vasculogenesis, and correcting the defects in dysfunctional EPC obtained from acute myocardial infarction (AMI) patients.
dc.relation.ispartof	Cardiovascular research, 2019, vol. 115, num. 2, p. 409-418
dc.subject	Medicina
dc.title	Microparticles Harboring Sonic Hedgehog Morphogen Improve the Vasculogenesis Capacity of Endothelial Progenitor Cells Derived from Myocardial Infarction Patients.
dc.type	journal article	es_ES
dc.date.updated	2020-03-27T09:04:47Z
dc.identifier.doi	10.1155/2019/4859082
dc.identifier.idgrec	129139
dc.rights.accessRights	open access	es_ES