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Measurement of body composition in cancer patients using CT planning scan at the third lumbar vertebra

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Measurement of body composition in cancer patients using CT planning scan at the third lumbar vertebra

dc.contributor.author	Muresan, Bianca T.
dc.contributor.author	Sánchez Juan, Carlos
dc.contributor.author	Artero, Ana
dc.contributor.author	Hernández Machancoses, Ana
dc.contributor.author	Almendros-Blanco, Piedad
dc.contributor.author	Montoro Pastor, Alegría
dc.contributor.author	Roselló Ferrando, Joan
dc.contributor.author	Íñigo Valdenebro, Rafael
dc.contributor.author	Ríos Ríos, Jaime
dc.contributor.author	Soriano del Castillo, José Miguel
dc.contributor.author	Quirante Cascales, J.V.
dc.contributor.author	López-Torrecilla, José
dc.date.accessioned	2020-03-31T11:50:08Z
dc.date.available	2020-03-31T11:50:08Z
dc.date.issued	2019
dc.identifier.citation	Muresan, Bianca T. Sánchez Juan, Carlos Artero, Ana Hernández Machancoses, Ana Almendros-Blanco, Piedad Montoro Pastor, Alegría Roselló Ferrando, Joan Íñigo Valdenebro, Rafael Ríos Ríos, Jaime Soriano del Castillo, José Miguel Quirante Cascales, J.V. López-Torrecilla, José 2019 Measurement of body composition in cancer patients using CT planning scan at the third lumbar vertebra Nutricion Hospitalaria 36 6 1307 1314
dc.identifier.uri	https://hdl.handle.net/10550/73726
dc.description.abstract	OBJECTIVE: the main objective was to assess body composition in terms of skeletal muscle index (SMI), myosteatosis, visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and intermuscular adipose tissue (IMAT) as an adjunct of information provided by radiotherapy CT planning scan. MATERIAL AND METHODS: a sample of 49 patients with lung and digestive cancers underwent a CT scan for radiotherapy treatment, which included measurements at the L3 region. Images were analyzed with a radiotherapy contouring software, using different Hounsfield Unit (HU) settings. Cross-sectional areas (cm2) were automatically computed by summing tissue pixels and multiplying by pixel surface area. Low SMI (cm2/m2) and muscle density (HU) were determined according to the recently established cut-off points. RESULTS: the prevalence of low SMI was detected in 46.94% of patients, being present in 8 women, 4 men with BMI < 25 kg/m2, and 11 men with BMI ≥ 25 kg/m2. The average mean skeletal attenuation of total skeletal muscle area was 29.02 (± 8.66) HU, and myosteatosis was present in 13 women (81.25%) and 31 men (93.94%). Mean SAT was 131.92 (± 76.80) cm2, mean VAT was 133.19 (± 85.28) cm2, and mean IMAT was 11.29 (± 12.86) cm2. CONCLUSION: skeletal muscle abnormalities are frequently present in cancer patients and a low SMI may also exist even in the presence of overweight. As CT scans are an important tool at any radiation oncology department, they could also be used to offer highly sensitive and specific information about body composition, as well as to detect early malnutrition before starting radiotherapy treatment.
dc.language.iso	eng
dc.relation.ispartof	Nutricion Hospitalaria, 2019, vol. 36, num. 6, p. 1307-1314
dc.subject	Radioteràpia
dc.subject	Càncer Pacients
dc.title	Measurement of body composition in cancer patients using CT planning scan at the third lumbar vertebra
dc.type	journal article	es_ES
dc.date.updated	2020-03-31T11:50:08Z
dc.identifier.doi	10.20960/nh.2435
dc.identifier.idgrec	137314
dc.rights.accessRights	open access	es_ES