NAGIOS: RODERIC FUNCIONANDO

Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles

Repositori DSpace/Manakin

Valencià Castellano

Inici
Investigació
e-prints
23 - Química
Visualitza element

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles

Mostra el registre parcial de l'element

dc.contributor.author	Montesinos Magraner, Marc
dc.contributor.author	Vila Descals, Carlos
dc.contributor.author	Blay Llinares, Gonzalo
dc.contributor.author	Fernández Picot, Isabel
dc.contributor.author	Muñoz, M. Carmen
dc.contributor.author	Pedro, José Ramón
dc.date.accessioned	2020-04-01T10:49:40Z
dc.date.available	2020-04-01T10:49:40Z
dc.date.issued	2017
dc.identifier.citation	Montesinos Magraner, Marc Vila Descals, Carlos Blay Llinares, Gonzalo Fernández Picot, Isabel Muñoz, M. Carmen Pedro, José Ramón 2017 Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles Organic Letters 19 7 1546 1549
dc.identifier.uri	https://hdl.handle.net/10550/73733
dc.description.abstract	A Cinchona-derived squaramide catalyzes the reaction between hydroxyindoles and isatins leading to enantioenriched indoles substituted in the carbocyclic ring. The reaction proceeds efficiently with differently substituted isatins, yielding the desired products with excellent regioselectivity, good yields, and high enantiocontrol. Moreover, every position of the carbocyclic ring of the indole can be functionalized by using the appropriate starting hydroxyindole. The OH group was removed smoothly upon hydrogenolysis of the corresponding triflate.
dc.language.iso	eng
dc.relation.ispartof	Organic Letters, 2017, vol. 19, num. 7, p. 1546-1549
dc.subject	Reaccions químiques
dc.subject	Catàlisi
dc.subject	Química orgànica
dc.title	Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles
dc.type	journal article	es_ES
dc.date.updated	2020-04-01T10:49:40Z
dc.identifier.doi	10.1021/acs.orglett.7b00354
dc.identifier.idgrec	116831
dc.rights.accessRights	open access	es_ES