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Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients : post-hoc analysis of LAS VEGAS study.

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Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients : post-hoc analysis of LAS VEGAS study.

dc.contributor.author	Robba, Chiara
dc.contributor.author	Hemmes, Sabrine N.T.
dc.contributor.author	Serpa Neto, Ary
dc.contributor.author	Bluth, Thomas
dc.contributor.author	Canet, Jaume
dc.contributor.author	Hiesmayr, Michael
dc.contributor.author	Hollmann, M. Wiersma
dc.contributor.author	Mills, Garty H.
dc.contributor.author	Vidal Melo, Marcos F.
dc.contributor.author	Putensen, Christian
dc.contributor.author	Jaber, Samir
dc.contributor.author	Schmid, Werner
dc.contributor.author	Severgnini, Paolo
dc.contributor.author	Wrigge, Hermann
dc.contributor.author	Battaglini, Denise
dc.contributor.author	Ball, Lorenzo
dc.contributor.author	Gama de Abreu, Marcelo
dc.contributor.author	Schultz, Marcus J.
dc.contributor.author	Pelosi, Paolo
dc.contributor.author	FERS for the LAS VEGAS investigators
dc.date.accessioned	2020-08-05T09:19:33Z
dc.date.available	2020-08-05T09:19:33Z
dc.date.issued	2020
dc.identifier.citation	Robba, Chiara Hemmes, Sabrine N.T. Serpa Neto, Ary Bluth, Thomas Canet, Jaume Hiesmayr, Michael Hollmann, M. Wiersma Mills, Garty H. Vidal Melo, Marcos F. Putensen, Christian Jaber, Samir Schmid, Werner Severgnini, Paolo Wrigge, Hermann Battaglini, Denise Ball, Lorenzo Gama de Abreu, Marcelo Schultz, Marcus J. Pelosi, Paolo FERS for the LAS VEGAS investigators 2020 Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients : post-hoc analysis of LAS VEGAS study. Bmc Anesthesiology 73 87
dc.identifier.uri	https://hdl.handle.net/10550/75417
dc.description.abstract	Background Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients. Methods Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs. Results Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs. Conclusions Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs.
dc.language.iso	eng
dc.relation.ispartof	Bmc Anesthesiology, 2020, p. 73-87
dc.subject	Pulmons Malalties
dc.subject	Cirurgia
dc.subject	Neurologia
dc.title	Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients : post-hoc analysis of LAS VEGAS study.
dc.type	journal article	es_ES
dc.date.updated	2020-08-05T09:19:33Z
dc.identifier.doi	10.1186/s12871-020-00988-x
dc.identifier.idgrec	140301
dc.rights.accessRights	open access	es_ES