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Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching

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Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching

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dc.contributor.author	Cardona-Maya, Y.
dc.contributor.author	Socorro, A. B.
dc.contributor.author	del Villar, I.
dc.contributor.author	Cruz Muñoz, José Luis
dc.contributor.author	Corres, J. M.
dc.contributor.author	Botero-Cadavid, J. F.
dc.date.accessioned	2020-10-06T07:06:41Z
dc.date.available	2020-10-06T07:06:41Z
dc.date.issued	july 2018	es_ES
dc.identifier.citation	Y. Cardona-Maya, A.B. Socorro, I. D. Villar, J.L. Cruz, J.M. Corres, J.F. Botero-Cadavid, "Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching," Sensors & Actuators: B. Chemical, Vol 265, pp. 10-19, 2018.	es_ES
dc.identifier.uri	https://hdl.handle.net/10550/75747
dc.description.abstract	The performance of E-SMS (Etched Singlemode-Multimode-Singlemode) optical fiber structures as immunosensors has been assessed by the implementation of antibody/antigen immunoassays. Through this procedure it has been proven that E-SMS structures are effective and suitable optical platforms for label-free biosensing. Using the phase shift and tracking the wavelength response it was found that the fabricated E-SMS devices exhibited limits of detection (LOD) down up to concentrations of 0.2 mg/L of antigens in solution. This was achieved by coating the E-SMS with an antibody-based biolayer (goat IgG) that is able to determine the presence of anti-goat IgG antigen. Both a wavelength detection and a fast Fourier transform (FFT) analysis technique were used to perform this analysis. The FFT method showed similar results to those observed with the most traditional wavelength analysis, but with the advantage of a simpler detection system that makes unnecessary the use of sophisticated optical interrogators.	es_ES
dc.language.iso	en	es_ES
dc.publisher	Elsevier	es_ES
dc.subject	optical fiber	es_ES
dc.subject	biosensor	es_ES
dc.subject	label-free	es_ES
dc.title	Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching	es_ES
dc.type	journal article	es_ES
dc.subject.unesco	220905	es_ES
dc.subject.unesco	230102	es_ES
dc.identifier.doi	10.1016/j.snb.2018.03.002	es_ES
dc.type.hasVersion	AM	es_ES