Primitive neuroectodermal kidney tumor
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Segura, Angel; Pérez, José; Reynes Muntaner, Gaspar; Yuste, Ana; Vera Sempere, Francisco José; Petschen, Ignacio
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Aquest document és un/a article, creat/da en: 2005
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To the Editor: Primitive neuroectodermal tumors (PNET) and Ewing sarcoma (ES) belong to a group of neoplasms de®ned by neuroectodermal differentiation and a characteristic cytogenetic translocation, t(11;22) (q24;q12) or gene rearrangements between chromosomes 21 and 22 [1]. They are generally aggressive tumors that present as metastatic disease in nearly 50% of the cases. ES is frequently a bone disease, whereas PNET can occur in bones, soft tissues, or any other site. Renal PNETs are extremely rare, with only a few cases reported [2]. We here record an adult with renal PNET and bone metastases at diagnosis. Because these tumor can also be found in children [3] our experience may therefore be helpful to pediatric oncologists |
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