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Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy

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Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy

dc.contributor.author	San Martín Valenzuela, Constanza
dc.contributor.author	Borras Barrachina, Aroa
dc.contributor.author	Gallego, Juan José
dc.contributor.author	Urios, Amparo
dc.contributor.author	Mestre Salvador, Víctor
dc.contributor.author	Correa Ghisays, Patricia María
dc.contributor.author	Ballester, María Pilar
dc.contributor.author	Escudero García, Desamparados
dc.contributor.author	Tosca, Joan
dc.contributor.author	Montón, Cristina
dc.contributor.author	Ríos, María Pilar
dc.contributor.author	Kosenko, Elena
dc.contributor.author	Felipo Orts, Vicente
dc.contributor.author	Tabarés Seisdedos, Rafael
dc.contributor.author	Selva Vera, Gabriel
dc.contributor.author	Montoliu, Carmina
dc.date.accessioned	2020-11-25T19:09:14Z
dc.date.available	2020-11-25T19:09:14Z
dc.date.issued	2020
dc.identifier.citation	San Martín Valenzuela, Constanza Borras Barrachina, Aroa Gallego, Juan José Urios, Amparo Mestre Salvador, Víctor Correa Ghisays, Patricia María Ballester, María Pilar Escudero García, Desamparados Tosca, Joan Montón, Cristina Ríos, María Pilar Kosenko, Elena Felipo, Vicente Tabares Seisdedos, Rafael Selva Vera, Gabriel Montoliu, Carmina 2020 Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy Journal Of Clinical Medicine
dc.identifier.uri	https://hdl.handle.net/10550/76493
dc.description.abstract	Minimal hepatic encephalopathy (MHE) is associated with mild cognitive impairment and frailty. This study aims to identify cognitive and motor differences in cirrhotic patients with and without MHE, and the correlations between motor signs and cognitive performance. Gait, balance, hand strength and motor speed performance were evaluated in 66 cirrhotic patients (38 without and 28 with MHE, according to the Psychometric Hepatic Encephalopathy Score (PHES). Cognitive performance was measured with the Mini-Mental State Examination, Verbal Fluency Test, Aprendizaje Verbal España-Complutense Test (TAVEC), Wechsler Adult Intelligence Scale III, Hamilton Depression and Anxiety Rating Scale and Functioning Assessment Short Test (FAST). MHE patients performed worse than patients without MHE in cognitive and autonomous functioning, learning and long-term memory, and verbal fluency. The same pattern was found in gait, center of pressure movement, variability of hand strength performance and hand motor speed. In MHE patients, high correlations were found between balance and FAST test, gait velocity and verbal skills, hand strength variability and anxiety and depression, and motor speed and FAST and TAVEC. MHE patients showed worse motor and cognitive performance than patients without MHE. MHE patients could have impaired movement control expressed as bradykinesia, and this reduced motor performance could correlate with cognitive performance.
dc.language.iso	eng
dc.relation.ispartof	Journal Of Clinical Medicine, 2020
dc.subject	Cirrosi hepàtica
dc.subject	Aprenentatge, Aptitud per a l' Tests
dc.subject	Aprenentatge motor
dc.title	Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy
dc.type	journal article	es_ES
dc.date.updated	2020-11-25T19:09:15Z
dc.identifier.doi	10.3390/jcm9072154
dc.identifier.idgrec	141482
dc.rights.accessRights	open access	es_ES