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Immunohistochemical and morphological characteristics of tissues response to polylactic acid membranes with silver nanoparticles

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Immunohistochemical and morphological characteristics of tissues response to polylactic acid membranes with silver nanoparticles

dc.contributor.author	Demyashkin, Grigory	es
dc.contributor.author	Kogan, Eugenia	es
dc.contributor.author	Borozdkin, Leonid	es
dc.contributor.author	Demura, Tatyana	es
dc.contributor.author	Shalamova, Elena	es
dc.contributor.author	Centroev, Zelimhan	es
dc.contributor.author	Ivanova, Irina	es
dc.contributor.author	Gevandova, Margarita	es
dc.contributor.author	Smirnova-Sotmari, Vlada	es
dc.contributor.author	Kalinin, Sergey	es
dc.date.accessioned	2021-01-14T10:11:37Z
dc.date.available	2021-01-14T10:11:37Z
dc.date.issued	2020	es
dc.identifier.citation	Demyashkin, Grigory ; Kogan, Eugenia ; Borozdkin, Leonid ; Demura, Tatyana ; Shalamova, Elena ; Centroev, Zelimhan ; Ivanova, Irina ; Gevandova, Margarita ; Smirnova-Sotmari, Vlada ; Kalinin, Sergey. Immunohistochemical and morphological characteristics of tissues response to polylactic acid membranes with silver nanoparticles. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 25 1 2020: 8-	es
dc.identifier.uri	https://hdl.handle.net/10550/77078
dc.description.abstract	The aim of this research was to study anti-microbial and anti-inflammatory characteristics of silver nanoparticles helping bone structures to recover during late stage of parodontitis, which afterwards will increase the effect of bone regeneration operations. We assessed colloid solution-derived silver nanoparticles coating of polylactic acid membrane regarding tissue foreign body response. Thirty eight polylactic acid membranes were implanted intracranially in rabbits ? ten unmodified (control group) and twenty eight with silver nanoparticles coating (experimental group). In controls, penicillin was used for infection prophylaxis. Tissue response was assessed by light microscopy and immunohistochemistry (CD3, CD15, CD30) 2 weeks after implantation. inflammation markers in experimental group were significantly lower than in control group, there were no signs of forming a fibrosis capsule nor infectious signs. colloid silver solution can be used as a source of nanoparticles for anti-microbial and anti-inflammatory biodegradable membranes? coating.	es
dc.title	Immunohistochemical and morphological characteristics of tissues response to polylactic acid membranes with silver nanoparticles	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.23171	es
dc.type.hasVersion	VoR	es_ES