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The impact of head and neck radiotherapy on the dentine-enamel junction : a systematic review

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The impact of head and neck radiotherapy on the dentine-enamel junction : a systematic review

dc.contributor.author	Fonsêca, Jéssica-Montenegro	es
dc.contributor.author	Troconis, Cristhian Camilo Madrid	es
dc.contributor.author	Palmier, Natalia	es
dc.contributor.author	Silva, Wagner-Gomes	es
dc.contributor.author	Paglioni, Mariana de Pauli	es
dc.contributor.author	Araújo, Anna Luiza Damaceno	es
dc.contributor.author	Arboleda, Lady Paola Aristizábal	es
dc.contributor.author	Filho, Aljomar José Vechiato	es
dc.contributor.author	González-Arriagada, Wilfredo-Alejandro	es
dc.contributor.author	Goes, Mario Fernando	es
dc.contributor.author	Lopes, Márcio Ajudarte	es
dc.contributor.author	Brandao, Thais-Bianca	es
dc.contributor.author	Vargas, Pablo Agustín	es
dc.contributor.author	Ribeiro, Ana-Carolina-Prado	es
dc.date.accessioned	2021-01-14T10:11:40Z
dc.date.available	2021-01-14T10:11:40Z
dc.date.issued	2020	es
dc.identifier.citation	Fonsêca, Jéssica-Montenegro ; Troconis, Cristhian Camilo Madrid ; Palmier, Natalia ; Silva, Wagner-Gomes ; Paglioni, Mariana de Pauli ; Araújo, Anna Luiza Damaceno ; Arboleda, Lady Paola Aristizábal ; Filho, Aljomar José Vechiato ; González-Arriagada, Wilfredo-Alejandro ; Goes, Mario Fernando ; Lopes, Márcio Ajudarte ; Brandao, Thais-Bianca ; Vargas, Pablo Agustín ; Ribeiro, Ana-Carolina-Prado. The impact of head and neck radiotherapy on the dentine-enamel junction : a systematic review. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 25 1 2020: 18-	es
dc.identifier.uri	https://hdl.handle.net/10550/77088
dc.description.abstract	Radiotherapy is widely used in contemporary head and neck cancer treatment protocols. The ability of head and neck radiotherapy (HNRT) to cause direct radiogenic destruction to the teeth is one of the most controversial topics in the field of oral oncology. Therefore, this systematic review aimed to investigate ionising radiation as an independent factor for physical and chemical changes on the dentine-enamel junction (DEJ), a pivotal dental topography for the onset and progression of radiation-related caries (RRC) and enamel delamination. Systematic searches were conducted on three databases: Scopus, MEDLINE (Via PubMed) and Embase (Elsevier). Laboratory studies evaluating the effects of simulated or in vivo HNRT on the DEJ were included. The GRADE tool adapted for in vitro studies was used to assess the methodological quality. Of the 154 initially selected studies, eight met the inclusion criteria, from which five studies were graded as high quality of evidence, two studies were graded as moderate quality and one as low quality. Two studies did not demonstrate DEJ alterations following HNRT while the other six articles described several organic and inorganic changes in the DEJ of irradiated teeth samples. These radiogenic events were mostly detected through micro and nanoindentation, Raman micro-spectroscopy, confocal microscopy, Western blotting and optical coherence tomography. HNRT may have a negative impact on the physical and chemical aspects of the DEJ, predisposing cancer patients to RRC and enamel delamination.	es
dc.title	The impact of head and neck radiotherapy on the dentine-enamel junction : a systematic review	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.23212	es
dc.type.hasVersion	VoR	es_ES