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miRNAs Regulation and Its Role as Biomarkers in Endometriosis.

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miRNAs Regulation and Its Role as Biomarkers in Endometriosis.

dc.contributor.author	Marí Alexandre, Josep
dc.contributor.author	Sánchez Izquierdo, Dolors
dc.contributor.author	Gilabert Estellés, Juan
dc.contributor.author	Barceló Molina, Moisés
dc.contributor.author	Braza-Boïls, Aitana
dc.contributor.author	Sandoval, Juan
dc.date.accessioned	2021-03-09T11:33:26Z
dc.date.available	2021-03-09T11:33:26Z
dc.date.issued	2016
dc.identifier.citation	Marí Alexandre, Josep Sánchez Izquierdo, Dolors Gilabert Estellés, Juan Barceló Molina, Moisés Braza-Boïls, Aitana Sandoval, Juan 2016 miRNAs Regulation and Its Role as Biomarkers in Endometriosis. International Journal Of Molecular Sciences 17 1
dc.identifier.uri	https://hdl.handle.net/10550/78210
dc.description.abstract	MicroRNAs (miRNAs) are small non-coding RNAs (18-22 nt) that function as modulators of gene expression. Since their discovery in 1993 in C. elegans, our knowledge about their biogenesis, function, and mechanism of action has increased enormously, especially in recent years, with the development of deep-sequencing technologies. New biogenesis pathways and sources of miRNAs are changing our concept about these molecules. The study of the miRNA contribution to pathological states is a field of great interest in research. Different groups have reported the implication of miRNAs in pathologies such as cancer, diabetes, cardiovascular, and gynecological diseases. It is also well-known that miRNAs are present in biofluids (plasma, serum, urine, semen, and menstrual blood) and have been proposed as ideal candidates as disease biomarkers. The goal of this review is to highlight the current knowledge in the field of miRNAs with a special emphasis to their role in endometriosis and the newest investigations addressing the use of miRNAs as biomarkers for this gynecological disease.
dc.language.iso	eng
dc.relation.ispartof	International Journal Of Molecular Sciences, 2016, vol. 17, num. 1
dc.subject	Ginecologia
dc.title	miRNAs Regulation and Its Role as Biomarkers in Endometriosis.
dc.type	journal article	es_ES
dc.date.updated	2021-03-09T11:33:27Z
dc.identifier.idgrec	124600
dc.rights.accessRights	open access	es_ES