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Changes in Salivary amylase and glucose in diabetes : a scoping review

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Changes in Salivary amylase and glucose in diabetes : a scoping review

dc.contributor.author	Pérez Ros, Pilar
dc.contributor.author	Navarro Flores, Emmanuel
dc.contributor.author	Julián Rochina, Iván
dc.contributor.author	Martínez Arnau, Francisco Miguel
dc.contributor.author	Cauli, Omar
dc.date.accessioned	2021-03-12T15:55:59Z
dc.date.available	2021-03-12T15:55:59Z
dc.date.issued	2021
dc.identifier.citation	Pérez Ros, Pilar Navarro Flores, Emmanuel Julián Rochina, Iván Martínez Arnau, Francisco Miguel Cauli, Omar 2021 Changes in Salivary amylase and glucose in diabetes : a scoping review Diagnostics 11 3
dc.identifier.uri	https://hdl.handle.net/10550/78286
dc.description.abstract	Background and Objective: Diabetes mellitus (DM) is a common long-term disease which can be related with salivary amylase levels. DM has recently been associated with salivary amylase diagnostics that could further impair diagnoses in the diabetic population, as well as being an interesting alternative to traditional methods of determine glucose levels. The main advantage of this method is related to the fact that it is a fast diagnostic method. The DM population experiences changes to their metabolism which affects their salivary parameters, making this an alternative procedure for diagnosis and follow-up of the illness due to the non-invasive nature of salivary analyzes. The objective of this review is to summarize the evidence regarding the changes in salivary amylase and glucose levels, and their relationship with blood markers of glycemic control used in clinical settings such as blood glucose and glycated hemoglobin. The differences in salivary amylase levels depending on the method of saliva collection under fasting or non-fasting conditions. The changes in salivary amylase depends on the type of diabetes, the type of insulin treatment or the quality of glycemic control. Conclusions: Salivary amylase concentration is increased in diabetic patients in most of the studies and salivary glucose concentration in all studies in both fasting and non-fasting (post-prandial) conditions. Salivary amylase and glucose concentration represent potential non-invasive biomarkers to evaluate glycemic control and clinical management of diabetic patients, although it is necessary to evaluate the influence of potential modulating factors such as age, duration diseases, sex and the effects of pharmacological treatments in these outcomes which remained to be elucidated.
dc.language.iso	eng
dc.relation.ispartof	Diagnostics, 2021, vol. 11, num. 3
dc.subject	Diabetis
dc.title	Changes in Salivary amylase and glucose in diabetes : a scoping review
dc.type	journal article	es_ES
dc.date.updated	2021-03-12T15:55:59Z
dc.identifier.doi	10.3390/diagnostics11030453
dc.identifier.idgrec	143948
dc.rights.accessRights	open access	es_ES