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Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy

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Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy

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dc.contributor.author	Lucherelli, Matteo Andrea
dc.contributor.author	Yu, Yue
dc.contributor.author	Reina, Giacomo
dc.contributor.author	Abellán Sáez, Gonzalo
dc.contributor.author	Miyako, Eijiro
dc.contributor.author	Bianco, Alberto
dc.date.accessioned	2021-04-26T14:45:41Z
dc.date.available	2021-04-26T14:45:41Z
dc.date.issued	2020
dc.identifier.citation	Lucherelli, Matteo Andrea Yu, Yue Reina, Giacomo Abellán Sáez, Gonzalo Miyako, Eijiro Bianco, Alberto 2020 Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy Angewandte Chemie 132 33 14138 14143
dc.identifier.uri	https://hdl.handle.net/10550/78920
dc.description.abstract	The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer activity. The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal properties prove the great advantage of a combined chemo‐ and phototherapy based on graphene against cancer, opening the doors to future therapeutic applications of this type of material.
dc.language.iso	eng
dc.relation.ispartof	Angewandte Chemie, 2020, vol. 132, num. 33, p. 14138-14143
dc.subject	Materials
dc.subject	Càncer
dc.title	Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy
dc.type	journal article	es_ES
dc.date.updated	2021-04-26T14:45:42Z
dc.identifier.doi	10.1002/ange.201916112
dc.identifier.idgrec	145990
dc.rights.accessRights	open access	es_ES