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The RNA World : piecing together the historical development of a hypothesis

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The RNA World : piecing together the historical development of a hypothesis

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dc.contributor.author Lazcano Araujo, Antonio es
dc.date.accessioned 2021-06-15T08:05:58Z
dc.date.available 2021-06-15T08:05:58Z
dc.date.issued 2016 es
dc.identifier.citation Lazcano Araujo, Antonio. The RNA World : piecing together the historical development of a hypothesis. En: Mètode Science Studies Journal: Annual Review, 6 2016: 166-173 es
dc.identifier.uri https://hdl.handle.net/10550/79737
dc.description.abstract The concept of an RNA world is a hypothesis firmly rooted in empirical data and is part of a long and complex scientific perspective that goes back more than fifty years to the discovery of the central role RNA and ribonucleotides play in protein synthesis and biochemical reactions took place. As the understanding of RNA biology progressed, several independent proposals of protein-free primordial life forms were suggested. Although this possibility was strongly reinforced with the discovery of ribozymes, there are many definitions of the RNA world, including several contradictory ones. One could say that it was an early, perhaps primordial, stage during which RNA molecules played a much more conspicuous role in heredity and metabolism and, particularly, in the origin and early evolution of protein biosynthesis. The overwhelming evidence for the catalytic, regulatory, and structural properties of RNA molecules, combined with their ubiquity in cellular processes, can only be explained with the proposal that they played a key role in early evolution and perhaps in the origin of life itself. es
dc.title The RNA World : piecing together the historical development of a hypothesis es
dc.type journal article es_ES
dc.subject.unesco es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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