NAGIOS: RODERIC FUNCIONANDO

The rotavirus vaccine landscape, an update

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

The rotavirus vaccine landscape, an update

dc.contributor.author	Cárcamo-Calvo, Roberto
dc.contributor.author	Muñoz Collado, Carlos
dc.contributor.author	Buesa Gómez, Javier
dc.contributor.author	Rodríguez Díaz, Jesús
dc.contributor.author	Gozalbo Rovira, Roberto Vicente
dc.date.accessioned	2021-07-16T13:25:59Z
dc.date.available	2021-07-16T13:25:59Z
dc.date.issued	2021
dc.identifier.citation	Cárcamo-Calvo, Roberto Muñoz Collado, Carlos Buesa Gómez, Javier Rodríguez Díaz, Jesús Gozalbo Rovira, Roberto Vicente 2021 The rotavirus vaccine landscape, an update Pathogens 10 520 1 15
dc.identifier.uri	https://hdl.handle.net/10550/79963
dc.description.abstract	Rotavirus is the leading cause of severe acute childhood gastroenteritis, responsible for more than 128,500 deaths per year, mainly in low-income countries. Although the mortality rate has dropped significantly since the introduction of the first vaccines around 2006, an estimated 83,158 deaths are still preventable. The two main vaccines currently deployed, Rotarix and RotaTeq, both live oral vaccines, have been shown to be less effective in developing countries. In addition, they have been associated with a slight risk of intussusception, and the need for cold chain maintenance limits the accessibility of these vaccines to certain areas, leaving 65% of children worldwide unvaccinated and therefore unprotected. Against this backdrop, here we review the main vaccines under development and the state of the art on potential alternatives.
dc.language.iso	eng
dc.relation.ispartof	Pathogens, 2021, vol. 10, num. 520, p. 1-15
dc.subject	Virus
dc.subject	Vacunació
dc.subject	Microorganismes patògens
dc.title	The rotavirus vaccine landscape, an update
dc.type	journal article	es_ES
dc.date.updated	2021-07-16T13:26:00Z
dc.identifier.doi	10.3390/pathogens10050520
dc.identifier.idgrec	147325
dc.rights.accessRights	open access	es_ES