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Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles

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Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles

dc.contributor.author	Bañó Polo, Manuel
dc.contributor.author	Martínez Gil, Luis
dc.contributor.author	Sánchez Del Pino, Manuel
dc.contributor.author	Massoli, Alberto
dc.contributor.author	Mingarro Muñoz, Ismael
dc.contributor.author	León, Rubén
dc.contributor.author	García Murria, María Jesús
dc.date.accessioned	2022-02-07T13:50:58Z
dc.date.available	2022-02-07T13:50:58Z
dc.date.issued	2022
dc.identifier.citation	Bañó Polo, Manuel Martínez Gil, Luis Sánchez Del Pino, Manuel Massoli, Alberto Mingarro Muñoz, Ismael León, Rubén García Murria, María Jesús 2022 Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles Journal Of Oral Microbiology 14 2030094
dc.identifier.uri	https://hdl.handle.net/10550/81515
dc.description.abstract	BACKGROUND: SARS-CoV-2 is continuously disseminating worldwide. The development of strategies to break transmission is mandatory. AIM OF THE STUDY: To investigate the potential of cetylpyridinium chloride (CPC) as a viral inhibitor. METHODS: SARS-CoV-2 Virus Like-Particles (VLPs) were incubated with CPC, a potent surfactant routinely included in mouthwash preparations. RESULTS: Concentrations of 0.05% CPC (w/v) commonly used in mouthwash preparations are sufficient to promote the rupture of SARS-CoV-2 VLP membranes. CONCLUSION: Including CPC in mouthwashes could be a prophylactic strategy to keep SARS-CoV-2 from spreading.
dc.language.iso	eng
dc.relation.ispartof	Journal Of Oral Microbiology, 2022, vol. 14, num. 2030094
dc.subject	Virologia
dc.subject	Microbiologia
dc.title	Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles
dc.type	journal article	es_ES
dc.date.updated	2022-02-07T13:50:59Z
dc.identifier.doi	10.1080/20002297.2022.2030094
dc.identifier.idgrec	150216
dc.rights.accessRights	open access	es_ES