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dc.contributor.author | Tarín, Juan José | |
dc.contributor.author | García Pérez, Miguel Ángel | |
dc.contributor.author | Cano, Antonio | |
dc.date.accessioned | 2022-02-17T14:23:47Z | |
dc.date.available | 2022-02-17T14:23:47Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Tarín, Juan José García Pérez, Miguel Ángel Cano, Antonio 2022 It Is Premature to Use Postmortem Sperm for Reproductive Purposes: a Data-Driven Opinion Reproductive Sciences vol. 29 3387-3393. | |
dc.identifier.uri | https://hdl.handle.net/10550/81675 | |
dc.description.abstract | Postmortem sperm retrieval for reproductive purposes is an assisted reproduction procedure that offers women an opportunity to have a child using sperm retrieved from their deceased partners. The ethical issues of this procedure have been discussed in previous works. However, an assessment of the procedure using a scientific perspective is still lacking. Here, we aim to ascertain, using a biological standpoint, whether postmortem sperm should be rescued for reproductive purposes. Data suggest that it is premature to use postmortem sperm for reproductive purposes. This procedure should not be clinically applied until appropriate and comprehensive analyses have been completed. Such analyses should be focused not only on fertilization, embryo development, and pregnancy outcomes, but also on potential postmortem alterations of sperm DNA, RNAs, and proteins. In addition, genetic and epigenetic analyses of sperm, pre-implantation embryos, and newborns, as well as mental and physical health follow-up of the resulting offspring during a whole life cycle, using appropriate non-human mammalian models, are warranted. | |
dc.language.iso | eng | |
dc.relation.ispartof | Reproductive Sciences, 2022 | |
dc.subject | Reproducció | |
dc.subject | RNA | |
dc.title | It Is Premature to Use Postmortem Sperm for Reproductive Purposes: a Data-Driven Opinion | |
dc.type | journal article | es_ES |
dc.date.updated | 2022-02-17T14:23:47Z | |
dc.identifier.doi | 10.1007/s43032-022-00874-6 | |
dc.identifier.idgrec | 150359 | |
dc.rights.accessRights | open access | es_ES |