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Somatostatin and Somatostatin Receptors: From Signaling to Clinical Applications in Neuroendocrine Neoplasms

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Somatostatin and Somatostatin Receptors: From Signaling to Clinical Applications in Neuroendocrine Neoplasms

dc.contributor.author	del Olmo García, María Isabel
dc.contributor.author	Prado-Wohlwend, Stefan
dc.contributor.author	Andres, Alexia
dc.contributor.author	Soriano del Castillo, José Miguel
dc.contributor.author	Bello, Pilar
dc.contributor.author	Merino Torres, Juan Francisco
dc.date.accessioned	2022-03-21T17:19:40Z
dc.date.available	2022-03-21T17:19:40Z
dc.date.issued	2021
dc.identifier.citation	del Olmo García, María Isabel Prado-Wohlwend, Stefan Andres, Alexia Soriano del Castillo, José Miguel Bello, Pilar Merino Torres, Juan Francisco 2021 Somatostatin and Somatostatin Receptors: From Signaling to Clinical Applications in Neuroendocrine Neoplasms Biomedicines 9 12 1810
dc.identifier.uri	https://hdl.handle.net/10550/81967
dc.description.abstract	Neuroendocrine neoplasms (NENs) are heterogeneous neoplasms which arise from neuroendocrine cells that are distributed widely throughout the body. Although heterogenous, many of them share their ability to overexpress somatostatin receptors (SSTR) on their cell surface. Due to this, SSTR and somatostatin have been a large subject of interest in the discovery of potential biomarkers and treatment options for the disease. The aim of this review is to describe the molecular characteristics of somatostatin and somatostatin receptors and its application in diagnosis and therapy on patients with NENs as well as the use in the near future of somatostatin antagonists.
dc.language.iso	eng
dc.relation.ispartof	Biomedicines, 2021, vol. 9, num. 12, p. 1810
dc.subject	Receptors d'hormones
dc.subject	Tumors
dc.title	Somatostatin and Somatostatin Receptors: From Signaling to Clinical Applications in Neuroendocrine Neoplasms
dc.type	journal article	es_ES
dc.date.updated	2022-03-21T17:19:40Z
dc.identifier.doi	10.3390/biomedicines9121810
dc.identifier.idgrec	149933
dc.rights.accessRights	open access	es_ES