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Salivary Testosterone and Cortisol as Biomarkers for the Diagnosis of Sarcopenia and Sarcopenic Obesity in Community-Dwelling Older Adults

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Salivary Testosterone and Cortisol as Biomarkers for the Diagnosis of Sarcopenia and Sarcopenic Obesity in Community-Dwelling Older Adults

dc.contributor.author	Diago-Galmés, Angela
dc.contributor.author	Guillamón-Escudero, Carlos
dc.contributor.author	Tenías Burillo, José María
dc.contributor.author	Soriano del Castillo, José Miguel
dc.contributor.author	Fernández Garrido, Julio Jorge
dc.date.accessioned	2022-03-21T17:41:19Z
dc.date.available	2022-03-21T17:41:19Z
dc.date.issued	2021
dc.identifier.citation	Diago-Galmés, Angela Guillamón-Escudero, Carlos Tenías Burillo, José María Soriano del Castillo, José Miguel Fernández Garrido, Julio Jorge 2021 Salivary Testosterone and Cortisol as Biomarkers for the Diagnosis of Sarcopenia and Sarcopenic Obesity in Community-Dwelling Older Adults Biology-Basel 10 2 93
dc.identifier.uri	https://hdl.handle.net/10550/81969
dc.description.abstract	Nowadays, the appearance of sarcopenia (S) or sarcopenic obesity (SO) is related to aging. According to the criteria of the European Working Group on Sarcopenia in Older People (EWGSOP), the feasibility of using salivary cortisol and testosterone levels was analyzed as diagnostic biomarkers of S or SO. One hundred and ninety non-institutionalized people aged ≥65 years were studied, independent of the activities of daily living (ADLs) (Barthel > 60), and sociodemographic variables were determined together with criteria for the diagnosis of S and SO including grip force, lower body strength, appendicular skeletal muscle mass, physical performance, total body fat percentage, body mass index (BMI), waist circumference, and triceps skinfold, together with the levels of salivary cortisol and testosterone. Our results reflected that women presented a higher prevalence of S and SO (21.2% and 30.2%, respectively). A significant difference was observed between salivary testosterone levels and the age of the participants with differences by sex. Testosterone values in men with S and SO were significantly lower (p = 0.043 and p = 0.048, respectively), which suggests a potential use of the biomarker for diagnostic purposes. No significant differences were shown with cortisol values.
dc.language.iso	eng
dc.relation.ispartof	Biology-Basel, 2021, vol. 10, num. 2, p. 93
dc.subject	Gerontologia
dc.subject	Obesitat
dc.title	Salivary Testosterone and Cortisol as Biomarkers for the Diagnosis of Sarcopenia and Sarcopenic Obesity in Community-Dwelling Older Adults
dc.type	journal article	es_ES
dc.date.updated	2022-03-21T17:41:19Z
dc.identifier.doi	10.3390/biology10020093
dc.identifier.idgrec	150669
dc.rights.accessRights	open access	es_ES