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The role of Vitamin D in early knee osteoarthritis and its relationship with their physical and psychological status

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The role of Vitamin D in early knee osteoarthritis and its relationship with their physical and psychological status

dc.contributor.author	Alabajos Cea, Ana
dc.contributor.author	Herrero Manley, Luz
dc.contributor.author	Suso Martí, Luis
dc.contributor.author	Viosca Herrero, Enrique
dc.contributor.author	Cuenca Martínez, Ferran
dc.contributor.author	Varangot Reille, Clovis
dc.contributor.author	Blanco Díaz, María
dc.contributor.author	Calatayud Villalba, Joaquín
dc.contributor.author	Casaña Granell, José
dc.date.accessioned	2022-04-13T13:10:48Z
dc.date.available	2022-04-13T13:10:48Z
dc.date.issued	2021
dc.identifier.citation	Alabajos Cea, Ana Herrero Manley, Luz Suso Martí, Luis Viosca Herrero, Enrique Cuenca Martínez, Ferran Varangot Reille, Clovis Blanco Díaz, María Calatayud Villalba, Joaquín Casaña Granell, José 2021 The role of Vitamin D in early knee osteoarthritis and its relationship with their physical and psychological status Nutrients
dc.identifier.uri	https://hdl.handle.net/10550/82343
dc.description.abstract	Osteoarthritis (OA) is a common joint condition and one of the greatest causes of disability worldwide. The role of vitamin D in the origin and development of the disease is not clear, although it could have important implications for diagnosis and treatment. For this proposal, a cross-sectional study with a non-probabilistic sample was performed. In total, 48 with early osteoarthritis (EOA) and 48 matched controls were selected, and serum 25(OH)D and parathyroid hormone (PTH) levels were analyzed. In addition, physical and psychological variables were measured to establish their relationship with vitamin D levels. Patients with EOA showed lower levels (22.3 ± 7.3 ng/mL) in comparison to matched controls (29.31 ± 9.2 ng/mL). A statistically significant higher number (Chi-squared = 8.525; p = 0.004) of patients with EOA had deficiency levels (<20 ng/mL) compared to the control group. Patients with lower vitamin D levels showed higher levels of pain intensity, disability, and anxiety, as well as poorer values for sit-to-stand, walking speed, and social participation. Correlation analysis showed a relationship between serum 25(OH)D, PTH and pain intensity, and social participation. These results highlight the relevance of vitamin D in the early diagnosis and prevention of EOA.
dc.language.iso	eng
dc.relation.ispartof	Nutrients, 2011
dc.subject	Vitamines
dc.subject	Artrosi
dc.subject	Genolls
dc.title	The role of Vitamin D in early knee osteoarthritis and its relationship with their physical and psychological status
dc.type	journal article	es_ES
dc.date.updated	2022-04-13T13:10:48Z
dc.identifier.doi	10.3390/nu13114035
dc.identifier.idgrec	151480
dc.rights.accessRights	open access	es_ES