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Comparative cytocompatibility and mineralization potential of Bio-C Sealer and TotalFill BC Sealer.

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Comparative cytocompatibility and mineralization potential of Bio-C Sealer and TotalFill BC Sealer.

dc.contributor.author	López-García, Sergio
dc.contributor.author	Pecci-Lloret, Miguel R.
dc.contributor.author	Guerrero Gironés, Julia
dc.contributor.author	Pecci-Lloret, María P.
dc.contributor.author	Lozano, Adrián
dc.contributor.author	Llena Puy, Maria Carmen
dc.contributor.author	Rodríguez Lozano, Francisco Javier
dc.contributor.author	Forner Navarro, Leopoldo
dc.date.accessioned	2022-05-16T11:31:35Z
dc.date.available	2022-05-16T11:31:35Z
dc.date.issued	2019
dc.identifier.citation	López-García, Sergio Pecci-Lloret, Miguel R. Guerrero Gironés, Julia Pecci-Lloret, María P. Lozano, Adrián Llena Puy, Maria Carmen Rodríguez Lozano, Francisco Javier Forner Navarro, Leopoldo 2019 Comparative cytocompatibility and mineralization potential of Bio-C Sealer and TotalFill BC Sealer. Materials 12 19 E3087
dc.identifier.uri	https://hdl.handle.net/10550/82784
dc.description.abstract	Abstract: The aim of this study was to investigate the cytocompatibility and mineralization potential of two premixed hydraulic endodontic sealers compared with an epoxy resin-based root canal sealer. The cellular responses and mineralization capacity were studied in human periodontal ligament stem cells (hPDLSCs) that were exposed to premixed hydraulic sealers, Bio-C Sealer (Angelus, Londrína, PR, Brazil), TotalFill BC Sealer (FKG Dentaire SA, La-Chaux-de-fonds, Switzerland) and an epoxy resin-based material, AH Plus (Dentsply De Trey, Konstanz, Germany). Non-exposed cultures served as the control. The endodontic sealers were assessed using scanning electron microscopy (SEM) and energy dispersive X-ray microanalysis (EDX). Statistical analyses were done using Analisis of Variance (ANOVA), with Bonferroni adjusted pairwise comparison (p = 0.05). AH Plus reduced cell viability and cell migration, whereas increased cell viability and cell migration were observed in the Bio-C Sealer and the TotalFill BC Sealer (p < 0.05). The lowest cell attachment and spreading were observed for all concentrations of AH Plus, whereas the highest were observed for TotalFill BC Sealer. At the end of 21 days, only the Bio-C Sealer and the TotalFill BC Sealer supported matrix mineralization (p < 0.05). Additionally, SEM-EDX revealed high content of calcium, oxygen, and silicon in the Bio-C Sealer and the TotalFill BC Sealer. Based on the results from this study, Bio-C Sealer and TotalFill BC Sealer demonstrated better cytocompatibility in terms of cell viability, migration, cell morphology, cell attachment, and mineralization capacity than AH Plus.
dc.language.iso	eng
dc.relation.ispartof	Materials, 2019, vol. 12, num. 19, p. E3087
dc.subject	Odontologia
dc.title	Comparative cytocompatibility and mineralization potential of Bio-C Sealer and TotalFill BC Sealer.
dc.type	journal article	es_ES
dc.date.updated	2022-05-16T11:31:36Z
dc.identifier.idgrec	137954
dc.rights.accessRights	open access	es_ES