NAGIOS: RODERIC FUNCIONANDO

Evolutionary distances corrected for purifying selection and ancestral polymorphisms

Repositori DSpace/Manakin

dc.contributor.author	Oteo-García, Gonzalo
dc.contributor.author	Oteo Araco, José Ángel
dc.date.accessioned	2022-05-16T14:36:44Z
dc.date.available	2022-05-16T14:36:44Z
dc.date.issued	2019
dc.identifier.citation	Oteo-García, Gonzalo Oteo Araco, José Ángel 2019 Evolutionary distances corrected for purifying selection and ancestral polymorphisms Journal of Theoretical Biology 483 110004
dc.identifier.uri	https://hdl.handle.net/10550/82789
dc.description.abstract	Evolutionary distance formulas that take into account effects due to ancestral polymorphisms and purifying selection are obtained on the basis of the full solution of Jukes-Cantor and Kimura DNA substitution models. In the case of purifying selection two different methods are developed. It is shown that avoiding the dimensional reduction implicitly carried out in the conventional model solving is instrumental to incorporate the quoted effects into the formalism. The problem of estimating the numerical values of the model parameters, as well as those of the correction terms, is not addressed.
dc.language.iso	eng
dc.relation.ispartof	Journal of Theoretical Biology, 2019, vol. 483, p. 110004
dc.subject	Evolució (Biologia)
dc.subject	Models biològics
dc.subject	ADN
dc.title	Evolutionary distances corrected for purifying selection and ancestral polymorphisms
dc.type	journal article	es_ES
dc.date.updated	2022-05-16T14:36:45Z
dc.identifier.doi	10.1016/j.jtbi.2019.110004
dc.identifier.idgrec	140300
dc.rights.accessRights	open access	es_ES