NAGIOS: RODERIC FUNCIONANDO

Coronavirus disease 2019 in chronic kidney disease

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Coronavirus disease 2019 in chronic kidney disease

dc.contributor.author	D'Marco, Luis
dc.contributor.author	Puchades Montesa, María Jesús
dc.contributor.author	Romero-Parra, Maria
dc.contributor.author	Gimenez-Civera, Elena
dc.contributor.author	Soler, Maria Jose
dc.contributor.author	Ortiz, Alberto
dc.contributor.author	Górriz Teruel, Jose Luis
dc.date.accessioned	2022-06-15T11:39:08Z
dc.date.available	2022-06-15T11:39:08Z
dc.date.issued	2020
dc.identifier.citation	D'Marco, Luis Puchades, Maria Jesus Romero-Parra, Maria Gimenez-Civera, Elena Soler, Maria Jose Ortiz, Alberto Gorriz Teruel, Jose Luis 2020 Coronavirus disease 2019 in chronic kidney disease CKJ: Clinical Kidney Journal 13 3 297 306
dc.identifier.uri	https://hdl.handle.net/10550/83153
dc.description.abstract	The clinical spectrum of coronavirus disease 2019 (COVID-19) infection ranges from asymptomatic infection to severe pneumonia with respiratory failure and even death. More severe cases with higher mortality have been reported in older patients and in those with chronic illness such as hypertension, diabetes or cardiovascular diseases. In this regard, patients with chronic kidney disease (CKD) have a higher rate of all-type infections and cardiovascular disease than the general population. A markedly altered immune system and immunosuppressed state may predispose CKD patients to infectious complications. Likewise, they have a state of chronic systemic inflammation that may increase their morbidity and mortality. In this review we discuss the chronic immunologic changes observed in CKD patients, the risk of COVID-19 infections and the clinical implications for and specific COVID-19 therapy in CKD patients. Indeed, the risk for severe COVID-19 is 3-fold higher in CKD than in non-CKD patients; CKD is 12-fold more frequent in intensive care unit than in non-hospitalized COVID-19 patients, and this ratio is higher than for diabetes or cardiovascular disease; and acute COVID19 mortality is 15-25% for haemodialysis patients even when not developing pneumonia.
dc.language.iso	eng
dc.relation.ispartof	CKJ: Clinical Kidney Journal, 2020, vol. 13, num. 3, p. 297-306
dc.subject	Virus
dc.title	Coronavirus disease 2019 in chronic kidney disease
dc.type	journal article	es_ES
dc.date.updated	2022-06-15T11:39:08Z
dc.identifier.doi	10.1093/ckj/sfaa104
dc.identifier.idgrec	154198
dc.rights.accessRights	open access	es_ES