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Bionate Lumbar Disc Nucleus Prosthesis : Biomechanical Studies in Cadaveric Human Spines

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Bionate Lumbar Disc Nucleus Prosthesis : Biomechanical Studies in Cadaveric Human Spines

dc.contributor.author	Vanaclocha-Saiz, Amparo
dc.contributor.author	Vanaclocha Vanaclocha, Vicente
dc.contributor.author	Atienza Vicente, Carlos M.
dc.contributor.author	Clavel, Pablo
dc.contributor.author	Jordá Gómez, P.
dc.contributor.author	Barrios, Carlos
dc.contributor.author	Sáiz-Sapena, Nieves
dc.contributor.author	Vanaclocha, Leyre
dc.date.accessioned	2023-02-14T17:28:37Z
dc.date.available	2023-02-14T17:28:37Z
dc.date.issued	2022
dc.identifier.citation	Vanaclocha-Saiz, Amparo Vanaclocha Vanaclocha, Vicente Atienza Vicente, Carlos M. Clavel, Pablo Jordá Gómez, P. Barrios, Carlos Sáiz-Sapena, Nieves Vanaclocha, Leyre 2022 Bionate Lumbar Disc Nucleus Prosthesis : Biomechanical Studies in Cadaveric Human Spines Acs Omega 7 50 46501 46514
dc.identifier.uri	https://hdl.handle.net/10550/85445
dc.description.abstract	Design: cadaveric spine nucleus replacement study. Objective: determining Bionate 80A nucleus replacement biomechanics in cadaveric spines. Methods: in cold preserved spines, with ligaments and discs intact, and no muscles, L3-L4, L4-L5, and L5-S1 nucleus implantation was done. Differences between customized and overdimensioned implants were compared. Flexion, extension, lateral bending, and torsion were measured in the intact spine, nucleotomy, and nucleus implantation specimens. Increasing load or bending moment was applied four times at 2, 4, 6, and 8 Nm, twice in increasing mode and twice in decreasing mode. Spine motion was recorded using stereophotogrammetry. Expulsion tests: cyclic compression of 50-550 N for 50,000 cycles, increasing the load until there was extreme flexion, implant extrusion, or anatomical structure collapse. Subsidence tests were done by increasing the compression to 6000 N load. Results: nucleotomy increased the disc mobility, which remained unchanged for the adjacent upper level but increased for the lower adjacent one, particularly in lateral bending and torsion. Nucleus implantation, compared to nucleotomy, reduced disc mobility except in flexion-extension and torsion, but intact mobility was no longer recovered, with no effect on upper or lower adjacent segments. The overdimensioned implant, compared to the customized implant, provided equal or sometimes higher mobility. Lamina, facet joint, and annulus removal during nucleotomy caused more damaged than that restored by nucleus implantation. No implant extrusion was observed under compression loads of 925-1068 N as anatomical structures collapsed before. No subsidence or vertebral body fractures were observed under compression loads of 6697.8-6812.3 N. Conclusions: nucleotomized disc and L1-S1 mobility increased moderately after cadaveric spine nucleus implantation compared to the intact status, partly due to operative anatomical damage. Our implant had shallow expulsion and subsidence risks.
dc.language.iso	eng
dc.relation.ispartof	Acs Omega, 2022, vol. 7, num. 50, p. 46501-46514
dc.subject	Columna vertebral
dc.subject	Ossos Malalties
dc.subject	Lumbàlgia
dc.title	Bionate Lumbar Disc Nucleus Prosthesis : Biomechanical Studies in Cadaveric Human Spines
dc.type	journal article	es_ES
dc.date.updated	2023-02-14T17:28:37Z
dc.identifier.doi	10.1021/acsomega.2c05294
dc.identifier.idgrec	156890
dc.rights.accessRights	open access	es_ES