Although fully automated vehicles (SAE level 5) are expected to acquire a major relevance for transportation dynamics by the next few years, the number of studies addressing their perceived benefits from the perspective of human factors remains substantially limited. This study aimed, firstly, to assess the relationships among drivers' demographic factors, their assessment of five key features of automated vehicles (i.e., increased connectivity, reduced driving demands, fuel and trip-related efficiency, and safety improvements), and their intention to use them, and secondly, to test the predictive role of the feature' valuations over usage intention, focusing on gender as a key differentiating factor. For this cross-sectional research, the data gathered from a sample of 856 licensed drivers (49.4% females, 50.6% males; M = 40.05 years), responding to an electronic survey, was analyzed. Demographic, driving-related data, and attitudinal factors were comparatively analyzed through robust tests and a bias-corrected Multi-Group Structural Equation Modeling (MGSEM) approach. Findings from this work suggest that drivers' assessment of these AV features keep a significant set of multivariate relationships to their usage intention in the future. Additionally, and even though there are some few structural similarities, drivers' intention to use an AV can be differentially explained according to their gender. So far, this research constitutes a first approximation to the intention of using AVs from a MGSEM gender-based approach, being these results of potential interest for researchers and practitioners from different fields, including automotive design, transport planning and road safety.