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Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater.

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Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater.

dc.contributor.author	Pérez Cataluña, Alba
dc.contributor.author	Chiner Oms, Álvaro
dc.contributor.author	Cuevas Ferrando, Enric
dc.contributor.author	Díaz Reolid, Azahara
dc.contributor.author	Falcó Ferrando, Irene Lourdes
dc.contributor.author	Randazzo, Walter
dc.contributor.author	Sánchez, Gloria
dc.date.accessioned	2023-05-25T11:28:41Z
dc.date.available	2023-05-25T11:28:41Z
dc.date.issued	2022
dc.identifier.citation	Pérez Cataluña, Alba Chiner Oms, Álvaro Cuevas Ferrando, Enric Díaz Reolid, Azahara Falcó Ferrando, Irene Lourdes Randazzo, Walter Sánchez, Gloria 2021 Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater. Water Research 211 1 8
dc.identifier.uri	https://hdl.handle.net/10550/86936
dc.description.abstract	Wastewater-based epidemiology (WBE) has proven to be an effective tool for epidemiological surveillance of SARS-CoV-2 during the current COVID-19 pandemic. Furthermore, combining WBE together with high-throughput sequencing techniques can be useful for the analysis of SARS-CoV-2 viral diversity present in a given sample. The present study focuses on the genomic analysis of SARS-CoV-2 in 76 sewage samples collected during the three epidemiological waves that occurred in Spain from 14 wastewater treatment plants distributed throughout the country. The results obtained demonstrate that the metagenomic analysis of SARS-CoV-2 in wastewater allows the detection of mutations that define the B.1.1.7 lineage and the ability of the technique to anticipate the detection of certain mutations before they are detected in clinical samples. The study proves the usefulness of sewage sequencing to track Variants of Concern that can complement clinical testing to help in decision-making and in the analysis of the evolution of the pandemic.
dc.language.iso	eng
dc.relation.ispartof	Water Research, 2021, vol. 211, p. 1-8
dc.subject	Aigües residuals Microbiologia
dc.subject	Microbiologia
dc.subject	Ecologia
dc.title	Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater.
dc.type	journal article
dc.date.updated	2023-05-25T11:28:42Z
dc.identifier.doi	10.1016/j.watres.2021.118007
dc.identifier.idgrec	159265
dc.rights.accessRights	open access