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Bioactive extracts from persimmon waste: influence of extraction conditions and ripeness.

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Bioactive extracts from persimmon waste: influence of extraction conditions and ripeness.

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dc.contributor.author Méndez, Daniel
dc.contributor.author Fabra Rovira, María José
dc.contributor.author Falcó Ferrando, Irene Lourdes
dc.contributor.author Sánchez, Gloria
dc.contributor.author Aranaz, Paula
dc.contributor.author Vettorazzi Armental, Ariane
dc.contributor.author López Rubio, Amparo
dc.date.accessioned 2023-05-25T16:10:33Z
dc.date.available 2023-05-25T16:10:33Z
dc.date.issued 2021
dc.identifier.citation Méndez, Daniel Fabra Rovira, María José Falcó Ferrando, Irene Lourdes Sánchez, Gloria Aranaz, Paula Vettorazzi Armental, Ariane López Rubio, Amparo 2021 Bioactive extracts from persimmon waste: influence of extraction conditions and ripeness. Food & Function 12 7428 7439
dc.identifier.uri https://hdl.handle.net/10550/86952
dc.description.abstract In this work, a bioactive persimmon extract was produced from discarded fruits. A central composite design was used to evaluate the effect of different extraction parameters and ripeness stages of persimmon fruits on the total phenolic content and antioxidant activity of the resulting extracts. Significantly greater phenolic contents were obtained from immature persimmon (IP) fruits. The optimum IP extract with the conditions set by the experimental design was industrially up-scaled and its composition and functional properties were evaluated and compared with those obtained under lab-scale conditions. Both extracts contained significant protein (>20%) and phenolic contents (∼11-27 mg GA/g dry extract) and displayed significant antiviral activity against murine norovirus and hepatitis A virus. Moreover, the extract showed no toxicity and significantly reduced the fat content and the cellular ageing of Caenorhabditis elegans (C. elegans) without affecting the worm development. These effects were mediated by down-regulation of fat-7, suggesting an anti-lipogenic activity of this extract.
dc.relation.ispartof Food & Function, 2021, vol. 12, p. 7428-7439
dc.subject Fruita
dc.subject Virus
dc.title Bioactive extracts from persimmon waste: influence of extraction conditions and ripeness.
dc.type journal article
dc.date.updated 2023-05-25T16:10:33Z
dc.identifier.doi 10.1039/D1FO00457C
dc.identifier.idgrec 159270
dc.rights.accessRights open access

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