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Prognostic implications of surgical specimen quality on the oncological outcomes of open and laparoscopic surgery in mid and low rectal cancer

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Prognostic implications of surgical specimen quality on the oncological outcomes of open and laparoscopic surgery in mid and low rectal cancer

dc.contributor.author	Pla Martí, Vicente
dc.contributor.author	Martín Arévalo, José
dc.contributor.author	Moro Valdezate, David
dc.contributor.author	García Botello, Stephanie Anne
dc.contributor.author	Pérez Santiago, Leticia
dc.contributor.author	Lapeña Rodríguez, María
dc.contributor.author	Bauzá Collado, Mireia
dc.contributor.author	Huerta, Marisol
dc.contributor.author	Roselló Keränen, Susana
dc.contributor.author	Espí Macías, Alejandro
dc.date.accessioned	2023-05-26T13:37:22Z
dc.date.available	2023-05-26T13:37:22Z
dc.date.issued	2021
dc.identifier.citation	Pla Martí, Vicente Martín Arévalo, José Moro Valdezate, David García Botello, Stephanie Anne Pérez Santiago, Leticia Lapeña Rodríguez, María Bauzá Collado, Mireia Huerta, Marisol Roselló Keränen, Susana Espí Macías, Alejandro 2021 Prognostic implications of surgical specimen quality on the oncological outcomes of open and laparoscopic surgery in mid and low rectal cancer Langenbecks Archives of Surgery 406 8 2759 2767
dc.identifier.uri	https://hdl.handle.net/10550/86988
dc.description.abstract	Purpose: Determine differences in pathologic outcomes between laparoscopic (LAP) and open surgery (OPEN) for mid and low rectal cancer and its influence in long-term oncological outcomes. Methods: Retrospective case matched study at a tertiary institution. Adults with rectal cancer below 12 cm from the anal verge operated between January 2005 and September 2018 were included. Primary outcomes were quality of specimen, overall survival (OS), disease-free survival (DFS), and local recurrence (LR). Results: The study included 311 patients, LAP = 108 (34.7%), OPEN = 203 (65,3%). A successful resection was accomplished in 81% of the LAP group and in 84.5% of the OPEN (p = 0.505). No differences in free distal margin (LAP = 100%, OPEN = 97.5%; p = 0.156) or circumferential resection margin (LAP = 95.2%, OPEN = 93.2%; p = 0.603) were observed. However, mesorectum quality was incomplete in 16.2% for LAP and in 8.1% for OPEN (p = 0.048). OS was 91.1% for LAP and 81.1% for OPEN (p = 0.360). DFS was 81.4% for LAP and 77.5% for OPEN (p = 0.923). Overall, LR was 2.3% without differences between groups. Conclusions: Laparoscopic approach could affect the quality of surgical specimen due to technical aspects. However, if principles of surgical oncology are respected, minor pathologic differences in the quality of the mesorectum may not influence on the long-term oncologic outcomes.
dc.language.iso	eng
dc.relation.ispartof	Langenbecks Archives of Surgery, 2021, vol. 406, num. 8, p. 2759-2767
dc.subject	Càncer Cirurgia
dc.subject	Recte Malalties
dc.title	Prognostic implications of surgical specimen quality on the oncological outcomes of open and laparoscopic surgery in mid and low rectal cancer
dc.type	journal article
dc.date.updated	2023-05-26T13:37:22Z
dc.identifier.doi	10.1007/s00423-021-02351-1
dc.identifier.idgrec	158419
dc.rights.accessRights	open access