The purpose of this study is to explore how tourism and hospitality firms managed marketing communica tions (marcom) since the COVID-19 outbreak and to propose a conceptual framework on marcom challenges that the pandemic crisis has brought to the industry. In-depth interviews were conducted with tourism and hospitality managers in Croatia, a destination that registered remarkable tourism results in 2021. The proposed conceptual framework reflects the adaptation process and major changes in B2C (business-to-consumer) and B2B (business-to-business) communication since the COVID-19 outbreak on one hand and resulting strategic opportunities for marcom managers on the other, discussed in terms of practical implications. To the best of the authors’ knowledge, this is the first study that presents an integrative overview of major chal lenges in marketing communications in tourism and hospitality since the COVID-19 outbreak by examining managers’ viewpoints through in-depth interviews. The study not only proposes a conceptual framework for understanding changes and opportunities that emerged in a situation of a systematic health emergency but also provides meaningful guidelines and implications for the global tourism and hospitality industry, as managers from many countries have been facing similar difficulties and challenges during the pandemic.