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A systematic review and meta-analysis on the effectiveness of xenograft to prevent periodontal defects after mandibular third molar extraction

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A systematic review and meta-analysis on the effectiveness of xenograft to prevent periodontal defects after mandibular third molar extraction

dc.contributor.author	Toledano-Serrabona, Jorge	es
dc.contributor.author	Ruiz Romero, Víctor	es
dc.contributor.author	Camps Font, Octavi	es
dc.contributor.author	Gay-Escoda, Cosme	es
dc.contributor.author	Sánchez-Garcés, María Ángeles	es
dc.date.accessioned	2023-06-16T08:36:41Z
dc.date.available	2023-06-16T08:36:41Z
dc.date.issued	2021	es
dc.identifier.citation	Toledano-Serrabona, J., Ruiz-Romero, V., Camps-Font, O., Gay-Escoda, C., & Sánchez-Garcés, MÁ. (2021). A systematic review and meta-analysis on the effectiveness of xenograft to prevent periodontal defects after mandibular third molar extraction. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e414-e421). Medicina Oral, S.L. https://doi.org/10.4317/medoral.24260	es
dc.identifier.uri	https://hdl.handle.net/10550/88040
dc.description.abstract	To evaluate the use of guided bone regeneration with xenograft to prevent periodontal defect in the distal aspect of the second molar after the surgical removal of the mandibular third molar. Three electronic databases (Pubmed, Cochrane Library and Scopus) were searched in April 2020. Randomized clinical trials in non-smokers and healthy patients, with at least six months follow-up, comparing periodontal probing depth, clinical attachment level, alveolar bone level and adverse events were selected by two independent investigators. The risk of bias assessment of the selected studies was evaluated by means of the Cochrane Collaboration?s Tool. Finally, a meta-analysis of the outcomes of interest was performed. Despite 795 articles were found in the initial search, only three randomized controlled clinical trials were included. Pooled results favoured the use of the xenograft plus collagen membrane over the spontaneous healing in terms of periodontal probing depth gain (MD=2.36; 95% CI 0.69 to 4.03; P=0.005) and clinical attachment level gain (MD=2.52; 95% CI 0.96 to 4.09; P=0.002). No other statistically significant differences were found. Within the limitations of the present review, the xenograft plus collagen membrane exhibited better periodontal results than spontaneous healing without increasing postoperative complications. However, future well-designed studies with larger samples are required to confirm our results.	es
dc.subject	biodentine	es
dc.subject	mta	es
dc.subject	retrograde filling	es
dc.subject	periapical surgery	es
dc.title	A systematic review and meta-analysis on the effectiveness of xenograft to prevent periodontal defects after mandibular third molar extraction	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.24260	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254883/