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Clinicopathologic features of nasopalatine duct cysts:a retrospective study in two Brazilian oral and maxillofacial pathology referral centers

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Clinicopathologic features of nasopalatine duct cysts:a retrospective study in two Brazilian oral and maxillofacial pathology referral centers

dc.contributor.author	Cavalcante, Israel Leal	es
dc.contributor.author	Barros, Caio-César-da Silva	es
dc.contributor.author	Cunha, John Lennon Silva	es
dc.contributor.author	Cruz, Vitória Maria Sousa	es
dc.contributor.author	Pedrosa, Gabriele Alves	es
dc.contributor.author	Santos, Amanda de Jesus	es
dc.contributor.author	Turatti, Eveline	es
dc.contributor.author	Albuquerque-Júnior, Ricardo-Luiz-Cavalcanti	es
dc.contributor.author	Cavalcante, Roberta Barroso	es
dc.date.accessioned	2023-06-16T08:36:44Z
dc.date.available	2023-06-16T08:36:44Z
dc.date.issued	2021	es
dc.identifier.citation	Cavalcante, IL., Barros, CC., Cunha, JL., Cruz, VM., Pedrosa, GA., Santos, Ad., Turatti, E., Albuquerque-Júnior, RL., & Cavalcante, RB. (2021). Clinicopathologic features of nasopalatine duct cysts: A retrospective study in two Brazilian oral and maxillofacial pathology referral centers. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e676-e683). Medicina Oral, S.L. https://doi.org/10.4317/medoral.24718	es
dc.identifier.uri	https://hdl.handle.net/10550/88074
dc.description.abstract	Nasopalatine duct cyst (NDC) is the most common non-odontogenic cyst in the oral cavity. Clinically it is not difficult to suspect these lesions based on clinical and radiographic appearance. However, the histopathological diagnosis may be difficult due to the broad morphological diversity of these lesions. The objective was to analyze the clinicopathological features of NDCs diagnosed in two oral and maxillofacial pathology services in the Brazilian northeast. A retrospective clinicopathologic study was performed. A total of 18,121 clinical records of oral lesions from two oral and maxillofacial pathology services in Brazil were analyzed (2000-2020). All NDCs cases were revised and demographic, clinical, radiographic, and histopathological data were collected. Among 18,121 diagnoses in the oral pathology services, 45 (0.2%) were NDCs. The series comprises 24 males (53.3%) and 21 females (46.7%), with a mean age of 43.2 years-old. Most lesions were asymptomatic (n = 27, 60%) with an mean size of 2.1 cm. Microscopically, the non-keratinized stratified squamous epithelium was the most common (66.7%). However, in 88.9% of cases, the epithelial lining was varied and composed of two or more types of epithelium. There was no significant association between the type of epithelium and the size of the cysts (p = 0.389). Nerve, blood vessels, hemorrhage, and chronic inflammatory infiltrate were commonly observed. In contrast, there was a low frequency of mucous glands, sebaceous glands, cholesterol clefts, and multinucleated giant cells. The clinical, radiographic, and microscopic findings observed in this study are similar to those reported in the literature. Due to the morphological diversity of NDC, it is needed to correlate its histopathological features with the clinical and radiographic findings to establish a correct diagnosis.	es
dc.subject	osteonecrosis of the jaw	es
dc.subject	recurrence	es
dc.subject	risk factor	es
dc.subject	bisphosphonates	es
dc.subject	zoledronic acid	es
dc.subject	denosumab	es
dc.subject	platelet rich plasma	es
dc.title	Clinicopathologic features of nasopalatine duct cysts:a retrospective study in two Brazilian oral and maxillofacial pathology referral centers	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.24718	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412456/