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HIV-related non-Hodgkin lymphomas affecting the oral cavity:a clinicopathologic study of 11 cases

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HIV-related non-Hodgkin lymphomas affecting the oral cavity:a clinicopathologic study of 11 cases

dc.contributor.author	Uchôa, Daniel Cavalléro Colares	es
dc.contributor.author	Corrêa Pontes, Flávia Sirotheau	es
dc.contributor.author	de Souza, Lucas-Lacerda	es
dc.contributor.author	dos Santos, Gabriela Sepêda	es
dc.contributor.author	Ribeiro, Ana-Carolina-Prado	es
dc.contributor.author	Brandao, Thais-Bianca	es
dc.contributor.author	Rodrigues-Oliveira, Leticia	es
dc.contributor.author	Gomes, Carolina Cavalieri	es
dc.contributor.author	Santos Silva, Alan Roger	es
dc.contributor.author	Fonseca, Felipe Paiva	es
dc.contributor.author	Almeida, Oslei Paes de	es
dc.contributor.author	Rebelo-Pontes, Hélder-Antônio	es
dc.date.accessioned	2023-06-16T08:36:47Z
dc.date.available	2023-06-16T08:36:47Z
dc.date.issued	2022	es
dc.identifier.citation	Uchôa, DC., Pontes, FS., Souza, LL., Santos, GS., Prado-Ribeiro, AC., Brandão, TB., Oliveira, LR., Gomes, CC., Santos-Silva, AR., Fonseca, FP., Almeida, FP., & Pontes, HA. (2022). HIV-related non-Hodgkin lymphomas affecting the oral cavity: a clinicopathologic study of 11 cases. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e99-e105). Medicina Oral, S.L. https://doi.org/10.4317/medoral.24993	es
dc.identifier.uri	https://hdl.handle.net/10550/88105
dc.description.abstract	HIV-related non-Hodgkin lymphomas of the oral cavity are rare lesions with aggressive clinical behaviour. The aim of this study is to describe the clinicopathological features of a series of HIV-related oral non-Hodgkin lymphomas. Eleven cases of oral lymphomas affecting HIV-positive patients were retrieved from 2012 to 2019. Clinicopathological features regarding age, sex, tumour location, clinical presentation, laboratory findings, disease stage and follow-up were obtained. Histologic, immunohistochemical and in situ hybridization for EBV detection were done for diagnosis confirmation. Overall survival was estimated by Kaplan?Meier curve. Males predominated, with a mean age of 40.3 years-old. Maxilla and mandible were the mostly affected. Plasmablastic lymphoma and diffuse large B-cell lymphoma not otherwise specified (NOS) were the main histological types. Lesions presented as reddish ulcerated swellings, representing the first sign of AIDS in six cases. Stage IV were common (7 cases) and the mean HIV viral load was 10,557 copies/mL, with a mean of 266 CD4+ cells/mm3, 1,278 CD8+ cells/mm3 and a CD4+/CD8+ ratio of 0.26. Eight patients died of the disease (72.7%). Overall survival revealed that 78.2% of the patients died after 21 months of follow-up. HIV-related oral lymphomas present a poor prognosis usually diagnosed in advanced stages and in our series plasmablastic lymphoma was the most common subtype.	es
dc.subject	dental caries	es
dc.subject	digital radiography	es
dc.subject	impacted tooth	es
dc.subject	panoramic radiography	es
dc.subject	third molar	es
dc.title	HIV-related non-Hodgkin lymphomas affecting the oral cavity:a clinicopathologic study of 11 cases	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.24993	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898576/