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Medication related to pigmentation of oral mucosa

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Medication related to pigmentation of oral mucosa

dc.contributor.author	Mallagray-Montero, María del Carmen	es
dc.contributor.author	Moreno López, Luis Alberto	es
dc.contributor.author	Cerero Lapiedra, Rocío	es
dc.contributor.author	Castro-Janeiro, María	es
dc.contributor.author	Madrigal Martínez-Pereda, Cristina	es
dc.date.accessioned	2023-06-16T08:36:48Z
dc.date.available	2023-06-16T08:36:48Z
dc.date.issued	2022	es
dc.identifier.citation	Mallagray-Montero, Md., Moreno-López, LA., Cerero-Lapiedra, R., Castro-Janeiro, M., & Madrigal-Martínez-Pereda, C. (2022). Medication related to pigmentation of oral mucosa. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e230-e237). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25110	es
dc.identifier.uri	https://hdl.handle.net/10550/88121
dc.description.abstract	The diagnosis of oral melanotic lesions is, more often than not, challenging in the clinical practice due to the fact that there are several reasons which may cause an increase in pigmentation on localized or generalized areas. Among these, medication stands out. In this work, we have carried out a review in the reference pharma database: Micromedex® followed by a review of the scientific published literature to analyse coincidences and possible discrepancies. Our findings show that there are several prescription drugs that can cause pigmented lesions in the oral mucosa. This must be known by clinicians in order to properly diagnose pigmented lesions. We have identified a set of 21 medicaments which cause these lesions, some of which are used frequently in the clinic, such as Metronidazole, Amitriptyline, conjugated oestrogens and Chlorhexidine gluconate. We also found discrepancies with the data published in specialized literature, some of which wasn?t reflected in the Summary of Product Characteristics. Our work highlights the importance of the proper communication of adverse drug reactions (ADR) by health professionals in order to provide thorough and accurate information and diagnosis.	es
dc.subject	mouth neoplasms	es
dc.subject	neoplasm invasiveness	es
dc.subject	blood vessels	es
dc.subject	peripheral nerves	es
dc.title	Medication related to pigmentation of oral mucosa	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25110	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054166/