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The evaluation of changes in maxillofacial bones using cone beam tomography in acromegaly

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The evaluation of changes in maxillofacial bones using cone beam tomography in acromegaly

dc.contributor.author	Dogruel, Fatma	es
dc.contributor.author	Canger, Emin Murat	es
dc.contributor.author	Gonen, Zeynep Burcin	es
dc.contributor.author	Asantogrol, Firdevs	es
dc.contributor.author	Sahin, Ali	es
dc.contributor.author	Bayram, Fahri	es
dc.date.accessioned	2023-06-16T08:36:49Z
dc.date.available	2023-06-16T08:36:49Z
dc.date.issued	2022	es
dc.identifier.citation	Dogruel, F., Canger, EM., Gonen, ZB., Asantogrol, F., Şahin, A., & Bayram, F. (2022). The evaluation of changes in maxillofacial bones using cone beam tomography in acromegaly. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e357-e365). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25280	es
dc.identifier.uri	https://hdl.handle.net/10550/88135
dc.description.abstract	The aim of the study was to evaluate the changes in craniofacial dimensions of newly diagnosed and untreated acromegaly patients, patients with non-functional pituitary adenoma and healthy individuals on Cone Beam Computed Tomography (CBCT). 50 newly diagnosed acromegaly patients who did not receive any treatment for acromegaly were included in the study (Group A). Twenty patients with nonfunctional pituitary adenoma (Group B) and 30 healthy individuals were included (Group C). Linear, angular and volumetric measurements were performed. Mandibular length showed significant difference in acromegaly patients, and maxillar length statistically significant difference was found between the A-B and B-C (p> 0,05), no difference was found between the A-C (p<0,05). SNB and ANB angle was statistically different in all groups, while SNA angle was statistically different between group A-C and B-C. In volumetric measurements, a statistically significant difference was found between groups a-c and groups A-B (p< 0,05), no difference was found between groups B-C (p>0,05). CBCT measurements showed that mandibular volume and length were increased in the acromegaly group compared to the group B-C. Present study is the first research that compares acromegaly patients in respect to changes in maxillofacial dimensions.	es
dc.subject	cx43	es
dc.subject	e-cadherin	es
dc.subject	ki67	es
dc.subject	bax	es
dc.subject	bcl-2	es
dc.subject	immunostaining expression profile	es
dc.subject	gja1 rs12197797 genotyping	es
dc.title	The evaluation of changes in maxillofacial bones using cone beam tomography in acromegaly	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25280	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271343/