NAGIOS: RODERIC FUNCIONANDO

Erythromycin:an alternative for the management of oral mucositis?

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Erythromycin:an alternative for the management of oral mucositis?

dc.contributor.author	Teixeira, Dieni-da Silveira	es
dc.contributor.author	Louzeiro, Gabriel Campos	es
dc.contributor.author	de Figueiredo, Maria-Antonia-Zancanaro	es
dc.contributor.author	Cherubini, Karen	es
dc.contributor.author	Salum, Fernanda-Gonçalves	es
dc.date.accessioned	2023-06-16T08:36:50Z
dc.date.available	2023-06-16T08:36:50Z
dc.date.issued	2022	es
dc.identifier.citation	Teixeira, DS., Louzeiro, GC., Figueiredo, MA., Cherubini, K., & Salum, FG. (2022). Erythromycin: an alternative for the management of oral mucositis? En Medicina Oral Patología Oral y Cirugia Bucal (pp. e452-e459). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25439	es
dc.identifier.uri	https://hdl.handle.net/10550/88143
dc.description.abstract	Oral mucositis (OM) is an important acute adverse effect of anticancer therapy. This condition presents high morbidity and may lead to the suspension of anticancer therapy. We reviewed the literature on the pathobiology of OM and the properties of erythromycin (EM), to consider the possibility of its use for the prevention and treatment of OM. We searched the PubMed, Scopus and Web of Science databases and selected complete articles published in English or Spanish that met the inclusion criteria. The search terms ?erythromycin?, ?inflammation?, ?immunomodulation? and ?oral mucositis? were used. The control of free radicals, transcription factors and pro-inflammatory cytokines has been considered as the key to the management of OM. EM has the ability to modulate oxidative stress, acts on the transcriptional system and inhibits the production of several cytokines that have been directly implicated in OM pathobiology. The present review suggests that EM could be effective in the treatment of OM. Experimental studies investigating the use of EM in OM should be encouraged.	es
dc.subject	gingiva	es
dc.subject	gingival diseases	es
dc.subject	gingival hyperplasia	es
dc.subject	oral pathology	es
dc.subject	diagnosis	es
dc.title	Erythromycin:an alternative for the management of oral mucositis?	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25439	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445611/