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Rhabdomyosarcoma of the head and neck in pediatric patients:a systematic review

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Rhabdomyosarcoma of the head and neck in pediatric patients:a systematic review

dc.contributor.author	Rodríguez Vargas, Mariana Paulina	es
dc.contributor.author	Villanueva Sánchez, Francisco G.	es
dc.date.accessioned	2023-06-16T08:36:52Z
dc.date.available	2023-06-16T08:36:52Z
dc.date.issued	2022	es
dc.identifier.citation	Rodríguez-Vargas, MP., & Villanueva-Sánchez, FG. (2022). Rhabdomyosarcoma of the head and neck in pediatric patients: a systematic review. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e569-e577). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25508	es
dc.identifier.uri	https://hdl.handle.net/10550/88163
dc.description.abstract	Rhabdomyosarcoma (RMS) is a soft tissue malignant tumor of mesenchymal cell origin, which usually shows variable differentiation of muscle cells. It is the most common solid sarcoma in children. The most usual site of occurrence are the head and neck regions. RMS presents a variety of histologic features, and so differential diagnosis with other small round cell tumors is needed. Hence, it has been very useful to the field to undertake additional immunohistochemical studies to determine the diagnosis and, on occasions, to assign subtype tumors. A systematic review of three databases (Medline, Biological Science Collection and Health & Medical Collection) was carried out with the purpose of analyzing rhabdomyosarcoma cases reported in the literature, specifically with localization in the head and neck regions in children. This strategy allowed us to identify the main anatomical site of appearance, the subtype of RMS, average age, histologic characteristics and immunohistochemistry markers used in a usual and any additional way. According to the selection criteria in this systematic review, twelve articles, and fourteen cases were identified that highlight that the histological diagnosis usually presents cellular heterogeneity. Therefore, immunohistochemistry is needed to confirm the diagnosis. Histologic characterization is not always sufficient for a conclusive diagnosis of RMS. Therefore, immunohistochemistry is helpful to determine the subtype and consequently, sometimes the behavior, treatment and prognosis. Additional markers may vary according to the institution and the need of particular cases.	es
dc.subject	coronary artery disease (cad)	es
dc.subject	periodontitis	es
dc.subject	non-surgical periodontal therapy (nspt)	es
dc.subject	periodontal treatment	es
dc.subject	periodontal therapy	es
dc.subject	meta-analysis	es
dc.title	Rhabdomyosarcoma of the head and neck in pediatric patients:a systematic review	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25508	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648637/