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Mucormycosis infection associated with global COVID-19 pandemic - an institutional histopathological study

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Mucormycosis infection associated with global COVID-19 pandemic - an institutional histopathological study

dc.contributor.author	Keerthika, R	es
dc.contributor.author	Narwal, Anjali	es
dc.contributor.author	Kamboj, Mala	es
dc.contributor.author	Devi, Anju	es
dc.contributor.author	Anand, Rahul	es
dc.contributor.author	Sivakumar, N	es
dc.contributor.author	Singh, Virendra	es
dc.contributor.author	Agarwal, Varsha	es
dc.contributor.author	Gupta, Ambika	es
dc.date.accessioned	2023-06-16T08:36:53Z
dc.date.available	2023-06-16T08:36:53Z
dc.date.issued	2023	es
dc.identifier.citation	Keerthika, R., Narwal, A., Kamboj, M., Devi, A., Anand, R., N, S., Singh, V., Agarwal, V., & Gupta, A. (2023). Mucor infection associated with global COVID-19 pandemic - an institutional histopathological study. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e99-e107). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25130	es
dc.identifier.uri	https://hdl.handle.net/10550/88179
dc.description.abstract	Coronavirus disease 2019 (COVID-19) in the recent times have instilled signs of immunosuppression globally which has further precipitated increasing range of opportunistic infections. Mucormycosis is a distressing opportunistic fungal infection with a high incidence and is the third commonest acute invasive infection following candidiasis and aspergillosis. The aim of the present observational study is to delineate the enigmatic histopathological profile between mucormycosis cases seen prior to pandemic (PPM) and pandemic associated mucormycosis (PAM). Tissue archives of 105 histopathologically diagnosed cases of mucormycosis were included and analysed for demographical details and histopathological parameters like fungal load and localization, granuloma formation, necrosis, inflammatory infiltrate and tissue invasion. 0ut of 105 included cases, 11/105 (10.48%) were reported PPM and 94/105 (89.52%) PAM. Among 94 cases of PAM, 51/94 (54%) cases also showed COVID-19 positivity, while 43/94 (46%) did not. Of all the histological variables, increased fungal load and necrosis were observed in PAM relative to PPM cases. The histopathological variables like fungal load, necrosis, granuloma formation and tissue invasion, could help the clinician in assessing the clinical status at the time of tissue diagnosis and improve the treatment accordingly.	es
dc.subject	articaine	es
dc.subject	dental implant	es
dc.subject	lidocaine	es
dc.subject	local anesthesia	es
dc.subject	mandibular nerve	es
dc.subject	pain perception	es
dc.title	Mucormycosis infection associated with global COVID-19 pandemic - an institutional histopathological study	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25130	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985935/