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Oral paracoccidioidomycosis:a retrospective study of 95 cases from a single center and literature review

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Oral paracoccidioidomycosis:a retrospective study of 95 cases from a single center and literature review

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dc.contributor.author Oliveira, Lucineide Lima Cardoso de es
dc.contributor.author Arruda, José A. es
dc.contributor.author Marinho, Marcia Frias Pinto es
dc.contributor.author Cavalcante, Israel Leal es
dc.contributor.author Abreu, Lucas G es
dc.contributor.author Corrêa-Abrahão, Aline es
dc.contributor.author Romañach, Mário José es
dc.contributor.author Andrade, Bruno Augusto Benevenuto de es
dc.contributor.author Agostini, Michelle es
dc.date.accessioned 2023-06-16T08:36:53Z
dc.date.available 2023-06-16T08:36:53Z
dc.date.issued 2023 es
dc.identifier.citation de Oliveira, LL., de Arruda, JA., Marinho, MF., Cavalcante, IL., Abreu, LG., Abrahão, AC., Romañach, MJ., de Andrade, BA., & Agostini, M. (2023). Oral paracoccidioidomycosis: a retrospective study of 95 cases from a single center and literature review. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e131-e139). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25613 es
dc.identifier.uri https://hdl.handle.net/10550/88183
dc.description.abstract The ecoepidemiological panorama of paracoccidioidomycosis (PCM) is dynamic and still ongoing in Brazil. In particular, data about the oral lesions of PCM are barely explored. The aim of this study was to report the clinicopathological features of individuals diagnosed with oral PCM lesions at an oral and maxillofacial pathology service in Rio de Janeiro, Brazil, in the light of a literature review. A retrospective study was conducted on oral biopsies obtained from 1958 to 2021. Additionally, electronic searches were conducted in PubMed, Embase, Scopus, Web of Science, Latin American and Caribbean Center on Health Sciences Information, and Brazilian Library of Dentistry to gather information from large case series of oral PCM. Ninety-five cases of oral PCM were surveyed. The manifestations were more frequent among males (n=86/90.5%), middle-aged/older adults (n=54/58.7%), and white individuals (n=40/51.9%). The most commonly affected sites were the gingiva/alveolar ridge (n=40/23.4%) and lip/labial commissure (n=33/19.3%); however, one (n=40/42.1%) or multiple sites (n=55/57.9%) could also be affected. In 90 (94.7%) patients, ?mulberry-like? ulcerations/moriform appearance were observed. Data from 21 studies (1,333 cases), mostly Brazilian (90.5%), revealed that men (92.4%; male/female: 11.8:1) and individuals in the fifth and sixth decades of life were the most affected (range: 7-89 years), with the gingiva/alveolar ridge, palate, and lips/labial commissure being the sites most frequently affected. The features of oral PCM lesions are similar to those reported in previous studies from Latin America. Clinicians should be aware of the oral manifestations of PCM, with emphasis on the clinicodemographic aspects and differential diagnoses, especially considering the phenomenon of the emergence of reported cases in rural and/or urban areas of Brazil. es
dc.subject oral cancer es
dc.subject paediatric es
dc.subject adolescent es
dc.subject epidemiology es
dc.subject head and neck neoplasms es
dc.subject biopsy es
dc.title Oral paracoccidioidomycosis:a retrospective study of 95 cases from a single center and literature review es
dc.type journal article es_ES
dc.subject.unesco UNESCO:CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.25613 es
dc.type.hasVersion VoR es_ES
dc.identifier.url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985941/

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