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Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial

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Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial

dc.contributor.author	Kaba, Yusuf Nuri	es
dc.contributor.author	Demirbas, Ahmet E	es
dc.contributor.author	Kütük, Nükhet	es
dc.contributor.author	Gunay Canpolat, Dilek	es
dc.contributor.author	Alkan, Alper	es
dc.date.accessioned	2023-06-16T08:36:54Z
dc.date.available	2023-06-16T08:36:54Z
dc.date.issued	2023	es
dc.identifier.citation	Kaba, YN., Demirbas, AE., Kütük, N., Canpolat, DG., & Alkan, A. (2023). Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e199-e207). Medicina Oral, S.L. https://doi.org/10.4317/medoral.24852	es
dc.identifier.uri	https://hdl.handle.net/10550/88191
dc.description.abstract	The purpose of this study was to evaluate the effect of a single-dose intravenous dexketoprofen administration for preventive analgesia on postoperative pain and reducing swelling in double jaw surgery. The authors designed a prospective, randomized, and double-blind cohort study. Patients who have Class III malocclusion were randomly divided in two groups. 50 mg intravenous dexketoprofen trometamol were administrated 30 minutes before incision in treatment group, while intravenous sterile saline was administrated 30 minutes before incision in placebo group. The primary predictor variable was treatment group. Primary outcomes were pain, swelling and 24-hour opioid intake. Patient- controlled analgesia with tramadol was given for management of postoperative pain. Other variables were demographic and operation related parameters. Visual analogue scale was used to evaluate postoperative pain. 3dMD Face System (3dMD, USA) was used to measure postoperative swelling. Data were analysed using two independent samples t test and Mann Whitney U test. The study sample was composed of 30 patients with a mean age of 20,63 years and 21 were female. Preemptive dexketoprofen administration decreased postoperative tramadol consumption by 25.9% compared to placebo group, and there was a statistically significant decrease in VAS scores (p<0,05). There was no statistically significant difference between the groups in terms of swelling (p>0,05). Preventive administration of intravenous dexketoprofen provides adequate analgesic effect in the postoperative 24-hour period and reduces opioid consumption in orthognathic surgery.	es
dc.subject	invisalign	es
dc.subject	surgery first	es
dc.subject	orthognathic surgery	es
dc.subject	periodontal health	es
dc.subject	quality of life	es
dc.title	Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.24852	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181024/