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Efficacy of stem cells in bone rehabilitation in patients with alveolar bone atrophy:a systematic review

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Efficacy of stem cells in bone rehabilitation in patients with alveolar bone atrophy:a systematic review

dc.contributor.author	Perez Leal, Martin	es
dc.contributor.author	Scanferla, Marta	es
dc.contributor.author	Carceller, María Carmen	es
dc.contributor.author	Flacco, Nicla	es
dc.date.accessioned	2023-06-16T08:36:55Z
dc.date.available	2023-06-16T08:36:55Z
dc.date.issued	2023	es
dc.identifier.citation	Pérez-Leal, M., Scanferla, M., Carceller, MC., & Flacco, N. (2023). Efficacy of stem cells in bone rehabilitation in patients with alveolar bone atrophy: a systematic review. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e247-e254). Medicina Oral, S.L. https://doi.org/10.4317/medoral.25667	es
dc.identifier.uri	https://hdl.handle.net/10550/88196
dc.description.abstract	Biomedical engineering proposes the use of stem cells as a bone rehabilitation treatment in patients with alveolar bone defects. Many authors suggest that this innovative technique could represent the future of bone regeneration in dentistry. The present study systematically reviewed the efficacy of stem cells in bone regeneration in patients with alveolar bone atrophy. Seven clinical trials in humans were included in this systematic review. In all the studies, the proposed objective of bone regeneration by using stem cells was achieved, although in a different way with different results. Although the authors of the analysed clinical trials achieved favourable results, they highlighted the presence of multiple limitations throughout bone regeneration treatments, such as scarce scientific literature on stem cells, a reduced number of follow-up studies, and a lack of a standardized international protocol. Based on the analysed studies, it is concluded that the therapy proposed by tissue engineering through the use of stem cells to rehabilitate patients with bone atrophies can be considered effective. In addition, the need for further studies and standardization of protocols is highlighted.	es
dc.subject	microinvasive	es
dc.subject	microinvasion	es
dc.subject	oral squamous cell carcinoma	es
dc.subject	oral cancer	es
dc.subject	histopathological profile	es
dc.subject	systematic review	es
dc.title	Efficacy of stem cells in bone rehabilitation in patients with alveolar bone atrophy:a systematic review	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO:CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.25667	es
dc.type.hasVersion	VoR	es_ES
dc.identifier.url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181026/