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Type of surgical treatment and recurrence of oral leukoplakia: A retrospective clinical study

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Type of surgical treatment and recurrence of oral leukoplakia: A retrospective clinical study

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dc.contributor.author Monteiro,Luís es
dc.contributor.author Barbieri,Cinzia es
dc.contributor.author Warnakulasuriya,Saman es
dc.contributor.author Martins,Marco es
dc.contributor.author Salazar,Filomena es
dc.contributor.author Pacheco,José-Júlio es
dc.contributor.author Vescovi,Paolo es
dc.contributor.author Meleti,Marco es
dc.date.accessioned 2023-06-22T12:12:35Z
dc.date.available 2023-06-22T12:12:35Z
dc.date.issued 2017 es
dc.identifier.citation Monteiro L, Barbieri C, Warnakulasuriya S, Martins M, Salazar F, Pacheco JJ, Vescovi P, Meleti M. Type of surgical treatment and recurrence of oral leukoplakia: A retrospective clinical study. Med Oral Patol Oral Cir Bucal. 2017 Sep 1;22 (5):e520-6. es
dc.identifier.uri https://hdl.handle.net/10550/88436
dc.description.abstract Background: Oral leukoplakia (OL) is the most typical potentially malignant disorder of the oral mucosa. We aimed to evaluate the clinical outcome of oral leukoplakia treated with several types of lasers and with the use of quantic molecular resonance (QMR) lancet, in terms of recurrence rate. Material and Methods: Eighty-seven previously untreated OL (52 occurring in females and 35 in males, mean age of 59.4 ± 13.9 years) were consecutively submitted to surgical treatment at University Hospital of Parma, Italy, and Hospital de Valongo, Portugal, (1999 to 2012). Interventions were subclassified into 5 groups according to the instrument used for the surgical removal of OL (cold blade – 17; Nd:YAG 1064nm laser – 14; Er:YAG 2940nm laser - 33; CO2 10600nm laser – 15; and QMR scalpel – 8). The mean follow-up period after treatment was 21.6 months (range 1-151 months). The outcome of treatment was scored through the same clinical protocol in the two participating units. Statistical analysis were carried by univariate analysis using chi-square test (or Pearson´s test when appropriate). Results: Recurrences were observed in 24 cases of OL (27.6%). Malignant transformation occurred in one patient (1.1%) after a period of 35 months. Statistical comparison of the 5 surgical treatment modalities showed no differences in clinical outcomes nor in the recurrence rate of OL. However, when Er:YAG laser group was compared with traditional scalpel, a significantly better outcome in cases treated with Er:YAG laser (P = 0.015) was highlighted. Conclusions: Our results suggests that Er:YAG laser could be a promising option for the treatment of OL. Key words:Oral leukoplakia; Potentially malignant disorders; Er:YAG Laser; CO2 Laser; Nd:YAG Laser; Quantic molecular resonance scalpel; malignant transformation rate. es
dc.title Type of surgical treatment and recurrence of oral leukoplakia: A retrospective clinical study es
dc.type journal article es_ES
dc.subject.unesco UNESCO:CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.21645 es
dc.type.hasVersion VoR es_ES

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