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Application of 5-Fluorouracil in management of glandular odontogenic cyst

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Application of 5-Fluorouracil in management of glandular odontogenic cyst

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dc.contributor.author Titinchi, Fadi es
dc.contributor.author Thompson, Junaid es
dc.contributor.author Ranchod, Sanjay es
dc.date.accessioned 2023-09-25T11:11:31Z
dc.date.available 2023-09-25T11:11:31Z
dc.date.issued 2023 es
dc.identifier.citation Titinchi, F., Thompson, J., & Ranchod, S. (2023). Application of 5-fluorouracil in management of glandular odontogenic cyst. Journal of Clinical and Experimental Dentistry, 15(6), 511-513 es
dc.identifier.uri https://hdl.handle.net/10550/89577
dc.description.abstract Glandular odontogenic cyst (GOC) is a rare, aggressive odontogenic lesion that presents in the jaws. It is a diagnostically challenging entity due to its ability to mimic intraosseous mucoepidermoid carcinoma, botryoid cyst, surgical ciliated cyst, and radicular cyst. Treatment ranges from conservative to aggressive surgical interventions due to its varied clinical and radiological appearance and also its potential for recurrence. Aggressive surgical interventions result in the need for surgical site reconstruction, thus increasing patient morbidity. We report a case of GOC in the anterior mandible that was conservatively treated by the application of 5-Fluorouracil (5-FU). Topical application of 5-FU was selected in the management of this lesion as it has shown to be effective in reducing recurrence rates of other aggressive odontogenic lesions such as odontogenic keratocysts. To our knowledge, this is the first case reported in the literature that was successfully treated by the combination of cyst enucleation, curettage, peripheral ostectomy and application of 5-FU. No recurrence was detected after 14-month follow-up. es
dc.subject Odontogenic cysts es
dc.subject Fluorouracil es
dc.subject Recurrence es
dc.title Application of 5-Fluorouracil in management of glandular odontogenic cyst es
dc.type journal article es_ES
dc.subject.unesco UNESCO:CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.60092 es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://www.medicinaoral.com/medoralfree01/aop/60092.pdf

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