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New insights into the composition of historical remedies and pharmaceutical formulations: the identification of natural resins and balsams by gas chromatographic-mass spectrometric investigations

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New insights into the composition of historical remedies and pharmaceutical formulations: the identification of natural resins and balsams by gas chromatographic-mass spectrometric investigations

dc.contributor.author	Izzo, Francesca Caterina
dc.contributor.author	Lodi, Giulia Carolina
dc.contributor.author	Vázquez de Ágredos-Pascual, María Luisa
dc.date.accessioned	2023-09-29T07:44:56Z
dc.date.available	2023-09-30T04:45:06Z
dc.date.issued	2021	es_ES
dc.identifier.citation	Izzo, F.C., Lodi, G.C. & Vázquez de Ágredos Pascual, M.L. New insights into the composition of historical remedies and pharmaceutical formulations: the identification of natural resins and balsams by gas chromatographic-mass spectrometric investigations. Archaeol Anthropol Sci 13, 2 (2021)	es_ES
dc.identifier.uri	https://hdl.handle.net/10550/89692
dc.description.abstract	The present paper reports one of the first studies on the identification of natural resins and balsams in modern era drug formulations. Gas chromatography coupled with mass spectrometry (GC-MS) was applied to investigate the composition of ancient remedies and pharmaceutical formulations coming from the Spezieria di Santa Maria della Scala in Rome, founded at the end of the seventeenth century by the Discalced Carmelites. The obtained results highlight the presence of complex mixtures containing resinaceous and lipidic-based compounds. Thanks to the detection of characteristic markers, it was possible to identify several natural resins, such as guaiacum resin, ladano resin and scammony resin. Balsamic and aromatic compounds characteristic of essential oils were identified as well. In addition, an anti-inflammatory ointment, composed by mixing Venetian turpentine, a Pinaceae resin and a triterpene resin exudate of a plant from South America, was found among the analysed formulations. Combining the analytical results, the historical research and the botanical composition, it was possible to formulate compositional hypotheses of this historical medicine and provided some indications about their use in health. The study of historical drugs is not only important to know the practices handed down by apothecaries in the past, but also fundamental to reconstruct historical recipes that can inspire new dermatological, cosmetic, hygienic and current curative products.	es_ES
dc.language.iso	en	es_ES
dc.publisher	Springer Link	es_ES
dc.subject	historical drugs	es_ES
dc.subject	Spezieria of Santa Maria della Scala in Rome	es_ES
dc.subject	natural organic compounds	es_ES
dc.subject	GC-MS	es_ES
dc.subject	resins	es_ES
dc.subject	balsams	es_ES
dc.title	New insights into the composition of historical remedies and pharmaceutical formulations: the identification of natural resins and balsams by gas chromatographic-mass spectrometric investigations	es_ES
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::ANTROPOLOGÍA	es_ES
dc.identifier.doi	10.1007/s12520-020-01236-6	es_ES
dc.accrualmethod	S	es_ES
dc.embargo.terms	0 days	es_ES
dc.type.hasVersion	VoR	es_ES
dc.rights.accessRights	open access	es_ES